tert-butyl 1,2,3,4-tetrahydroquinoline-3-carboxylate CAS 177202-65-2
| CAS No. | 177202-65-2 |
| Molecular Formula | C14H19NO2 |
| Molecular Weight | 233.31 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
tert-butyl 1,2,3,4-tetrahydroquinoline-3-carboxylate (CAS 177202-65-2) is a high-purity analytical reference standard with the molecular formula C14H19NO2 and a molecular weight of 233.31 g/mol.
The molecular framework of tert-butyl 1,2,3,4-tetrahydroquinoline-3-carboxylate (C14H19NO2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C14H19NO2 |
| Molecular Weight | 233.31 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2007 |
| Nitrogen Atoms | 1 |
Recommended Standards
- Methyl N-benzyl-N-(but-3-en-1-yl)glycinate (CAS 175227-10-8)
- 3-(4-(Dimethylamino)piperidin-1-yl)isonicotinaldehyde (CAS 1774895-14-5)
- 2-[2-(Dimethylamino)ethyl]-2,3-dihydro-5-methoxy-1H-inden-1-one (CAS 173070-28-5)
- 5-(4-(Dimethylamino)piperidin-1-yl)nicotinaldehyde (CAS 1774897-37-8)
- tert-Butyl 2-(phenylmethoxycarbonylamino)-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazine-5-carboxylate (CAS 1209488-61-8)
- 3-Isopropyl-2-methyl-6-(trifluoromethyl)quinolin-4-ol (CAS 1707373-33-8)
- 4,6-Difluoro-2-(piperazin-1-yl)pyrimidine (CAS 675588-43-9)
- (2S,3R,4R,5R)-5-(benzyloxymethyl)-3-[tert-butyl(dimethyl)silyl]oxy-tetrahydrofuran-2,4-diol (CAS 1583259-70-4)
- Loganic Acid (CAS 22255-40-9)
- 5-(P-tolyl)isoxazol-3-amine (CAS 911052-40-9)
- Isopropyl 1,3-dioxo-2-(m-tolyl)isoindoline-5-carboxylate (CAS 53207-37-7)
- 5-(Ethylsulfonyl)-1H-indole (CAS 193900-08-2)
- 2-(Benzyloxy)-3-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine (CAS 1375302-97-8)
- Peptide Impurity 27 (CAS 1350456-68-6)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com