Isopropyl 1-(difluoromethyl)-3,3-dimethoxycyclobutanecarboxylate CAS 1773508-52-3
| CAS No. | 1773508-52-3 |
| Molecular Formula | C11H18F2O4 |
| Molecular Weight | 252.26 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Isopropyl 1-(difluoromethyl)-3,3-dimethoxycyclobutanecarboxylate (CAS 1773508-52-3) is a high-purity analytical reference standard with the molecular formula C11H18F2O4 and a molecular weight of 252.26 g/mol.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, Isopropyl 1-(difluoromethyl)-3,3-dimethoxycyclobutanecarboxylate is typically white to off-white crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 252.26 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H18F2O4 |
| Molecular Weight | 252.26 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1994 |
| Halogen Content | F-containing |
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Recommended Standards
- 4-(4-Acetyl-2-methoxyphenoxy)butanoic acid (CAS 174884-22-1)
- (2R)-2-Methyl-2-(phenylmethoxy)propanedioic Acid 1-Ethyl Ester (CAS 1786-91-0)
- 2-Methoxy-3-methylanthracene-9,10-dione (CAS 17241-42-8)
- Ethyl 2-acetoxy-3-(2-hydroxyphenyl)propanoate (CAS 1799611-05-4)
- (R)-Oxirane-2-carboxylic acid (CAS 115005-76-0)
- Methyl 5-{[(5-sulfanyl-1,3,4-thiadiazol-2-yl)sulfanyl]methyl}furan-2-carboxylate (CAS 790270-68-7)
- 2,2,3,3,4,4,4-Heptafluorobutyl isopropyl carbonate (CAS 1923065-19-3)
- 4-(methylamino)oxane-4-carboxylic acid (CAS 1157932-08-5)
- 3-Cyclohexyl-1-phenyl-1H-pyrazol-5-amine (CAS 1152711-96-0)
- Methyl 3-Oxo-3-(m-tolyl)propionate (CAS 200404-35-9)
- CAS 129212-37-9 (CAS 129212-37-9)
- 322647-32-5 Sodium (2R)-2,3-bis(pentadecanoyloxy)propyl 2,3-dihydroxypropyl phosphate DTXSID10677101 (CAS 322647-32-5)
- 2-(Pyrimidin-4-yl)benzoic acid hydrochloride (CAS 1429505-74-7)
- Semaglutide impurity 274 (CAS CATO-C4X-2226274)
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