1-(4-Bromo-2-(trifluoromethyl)phenyl)-3,3-difluoropyrrolidine CAS 1774895-87-2

Description

The occurrence of 1-(4-Bromo-2-(trifluoromethyl)phenyl)-3,3-difluoropyrrolidine is closely related to a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/bromine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

CATO supplies 1-(4-Bromo-2-(trifluoromethyl)phenyl)-3,3-difluoropyrrolidine (CAS 1774895-87-2), a certified reference material (molecular formula C11H9BrF5N, MW 330.09 g/mol) for analytical method development and quality control.

The molecular framework of 1-(4-Bromo-2-(trifluoromethyl)phenyl)-3,3-difluoropyrrolidine (C11H9BrF5N) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/bromine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Why CATO?

• ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
• 130,000+ catalog items in stock, COA supplied with every batch
• Worldwide shipping with full export documentation (HS code guidance available)
• Technical support: +86 18665070610 / Nicole.chen@cato-chem.com