5-Chloro-3-(2,2,2-trifluoroethoxy)thiophene-2-carboxylic acid CAS 1774902-56-5

Description

The occurrence of 5-Chloro-3-(2,2,2-trifluoroethoxy)thiophene-2-carboxylic acid is closely related to a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

5-Chloro-3-(2,2,2-trifluoroethoxy)thiophene-2-carboxylic acid (CAS 1774902-56-5) is a high-purity analytical reference standard with the molecular formula C7H4ClF3O3S and a molecular weight of 260.62 g/mol.

The molecular framework of 5-Chloro-3-(2,2,2-trifluoroethoxy)thiophene-2-carboxylic acid (C7H4ClF3O3S) is characterized by a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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