1-{4-[2-methyl-6-(trifluoromethyl)pyrimidin-4-yl]piperazin-1-yl}-2-phenoxyethan-1-one CAS 1775331-97-9
| CAS No. | 1775331-97-9 |
| Molecular Formula | C18H19F3N4O2 |
| Molecular Weight | 380.36 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
1-{4-[2-methyl-6-(trifluoromethyl)pyrimidin-4-yl]piperazin-1-yl}-2-phenoxyethan-1-one (CAS 1775331-97-9), molecular formula C18H19F3N4O2 and molecular weight 380.36 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, 1-{4-[2-methyl-6-(trifluoromethyl)pyrimidin-4-yl]piperazin-1-yl}-2-phenoxyethan-1-one is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 380.36 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO manufactures 1-{4-[2-methyl-6-(trifluoromethyl)pyrimidin-4-yl]piperazin-1-yl}-2-phenoxyethan-1-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C18H19F3N4O2 |
| Molecular Weight | 380.36 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1994 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
Related methyl Standards
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- 4-(((Trifluoromethyl)sulfonyl)oxy)-2H-chromen-7-yl pivalate (CAS 2226904-90-9)
- 10-[(E)-2-{[4-(trifluoromethyl)phenyl]amino}ethenyl]-2,3,7,11-tetraazatricyclo[7.4.0.0^{2,6}]trideca-1(9),3,5,7,10,12-hexaene-5-carbonitrile (CAS 338966-88-4)
- 3-{[5,7-bis(trifluoromethyl)[1,8]naphthyridin-2-yl]sulfanyl}-1H-1,2,4-triazol-5-amine (CAS 339026-17-4)
- 2-[3,5-bis(trifluoromethyl)benzoyl]benzoyl chloride (CAS 648859-58-9)
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Recommended Standards
- N-[(Dimethylamino)methylene]-2,3-O-(methoxymethylene)guanosine (CAS 1315092-28-4)
- 4-[4-(2-Methoxybenzoyl)piperazin-1-yl]-2-methyl-6-(trifluoromethyl)pyrimidine (CAS 1775364-80-1)
- O-Dimethylaminocarbonyl-4-(6-dimethylamino-4-trifluoromethylpyridin-2-yl)benzaldehyde oxime (CAS 1311283-83-6)
- N-(4-Methoxyphenyl)-1-[6-(trifluoromethyl)pyrimidin-4-yl]piperidine-4-carboxamide (CAS 1775443-54-3)
- N-(3,4-difluorobenzyl)-N-methylpyrrolidin-3-amine (CAS 1343062-29-2)
- 1-[4-(4-Piperidinylmethoxy)phenyl]-1-ethanonehydrochloride (CAS 1220021-33-9)
- (4-Fluoro-2-methyl[1,1-biphenyl]-3-yl)-methanamine (CAS 946714-22-3)
- 2-Cyclohexyl-2-oxoacetic acid (CAS 4354-49-8)
- 3,3-Diethyl-1-propylpiperidine-2,4-dione (CAS 698388-71-5)
- 2H-Cyclohepta[b]furan-2-one (CAS 4481-35-0)
- 6-(Chloromethyl)-2,3,4,5-tetrahydro-1,2,4-triazine-3,5-dione (CAS 24753-63-7)
- tert-butyl 3-(5-bromo-6-chloro-3-pyridyl)-3-methyl-piperazine-1-carboxylate (CAS 2357323-70-5)
- 4-(3-Trifluoromethoxyphenyl)benzoic Acid (CAS 1093758-81-6)
- Semaglutide Impurity 192 (CAS CATO-C4X-2226192)
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