2-[4-(5-Methyl-1,2,4-oxadiazol-3-yl)-1,3-dioxo-1H,2H,3H,5H,6H,7H,8H,9H-pyrimido[1,6-a]azepin-2-yl]-N-(4-methylphenyl)acetamide CAS 1775338-17-4
| CAS No. | 1775338-17-4 |
| Molecular Formula | C21H23N5O4 |
| Molecular Weight | 409.44 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO supplies 2-[4-(5-Methyl-1,2,4-oxadiazol-3-yl)-1,3-dioxo-1H,2H,3H,5H,6H,7H,8H,9H-pyrimido[1,6-a]azepin-2-yl]-N-(4-methylphenyl)acetamide (CAS 1775338-17-4), a certified reference material (molecular formula C21H23N5O4, MW 409.44 g/mol) for analytical method development and quality control.
The molecular framework of 2-[4-(5-Methyl-1,2,4-oxadiazol-3-yl)-1,3-dioxo-1H,2H,3H,5H,6H,7H,8H,9H-pyrimido[1,6-a]azepin-2-yl]-N-(4-methylphenyl)acetamide (C21H23N5O4) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO manufactures 2-[4-(5-Methyl-1,2,4-oxadiazol-3-yl)-1,3-dioxo-1H,2H,3H,5H,6H,7H,8H,9H-pyrimido[1,6-a]azepin-2-yl]-N-(4-methylphenyl)acetamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C21H23N5O4 |
| Molecular Weight | 409.44 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1994 |
| Nitrogen Atoms | 5 |
Related Methyl Standards
- 2-[4-(5-Methyl-1,2,4-oxadiazol-3-yl)-1,3-dioxo-1H,2H,3H,5H,6H,7H,8H,9H-pyrimido[1,6-a]azepin-2-yl]-N-(3-methylphenyl)acetamide (CAS 1775354-21-6)
- 2-[4-(5-Methyl-1,2,4-oxadiazol-3-yl)-1,3-dioxo-1H,2H,3H,5H,6H,7H,8H,9H-pyrimido[1,6-a]azepin-2-yl]-N-(2-methylphenyl)acetamide (CAS 1775444-53-5)
- 2-[4-(5-Ethyl-1,2,4-oxadiazol-3-yl)-1,3-dioxo-1H,2H,3H,5H,6H,7H,8H,9H-pyrimido[1,6-a]azepin-2-yl]-N-phenylacetamide (CAS 1775507-88-4)
- 2-[4-(5-Methyl-1,2,4-oxadiazol-3-yl)-1,3-dioxo-1H,2H,3H,5H,6H,7H,8H-pyrido[1,2-c]pyrimidin-2-yl]-N-[(4-methylphenyl)methyl]acetamide (CAS 1775524-00-9)
- 2-((5-(3-Phenyl-1,2,4-oxadiazol-5-yl)pyridin-2-yl)thio)-N-(thiophen-2-ylmethyl)acetamide (CAS 1251704-26-3)
- 2-[4-(5-Ethyl-1,2,4-oxadiazol-3-yl)-1,3-dioxo-1H,2H,3H,5H,6H,7H,8H-pyrido[1,2-c]pyrimidin-2-yl]-N-(3-fluorophenyl)acetamide (CAS 1775404-17-5)
- 4-(5-Ethyl-1,2,4-oxadiazol-3-yl)-2-[3-(4-fluorophenoxy)propyl]-1H,2H,3H,5H,6H,7H,8H-pyrido[1,2-c]pyrimidine-1,3-dione (CAS 1775345-18-0)
- 2-((5-Benzyl-1,3,4-oxadiazol-2-yl)thio)-N-(4-bromophenyl)acetamide (CAS 220597-89-7)
Recommended Standards
- N-(2-Ethylphenyl)-2-[4-(5-methyl-1,2,4-oxadiazol-3-yl)-1,3-dioxo-1H,2H,3H,5H,6H,7H,8H-pyrido[1,2-c]pyrimidin-2-yl]acetamide (CAS 1775336-96-3)
- N-Benzyl-2-[4-(5-ethyl-1,2,4-oxadiazol-3-yl)-1,3-dioxo-1H,2H,3H,5H,6H,7H,8H-pyrido[1,2-c]pyrimidin-2-yl]acetamide (CAS 1775345-47-5)
- N-(2,5-Dimethylphenyl)-2-[4-(5-methyl-1,2,4-oxadiazol-3-yl)-1,3-dioxo-1H,2H,3H,5H,6H,7H,8H-pyrido[1,2-c]pyrimidin-2-yl]acetamide (CAS 1775308-37-6)
- 4,5-Bis((4-methoxybenzyl)oxy)picolinohydrazide (CAS 161188-00-7)
- (4-(4-Bromophenyl)-1H-pyrrol-3-yl)(phenyl)methanol (CAS 338413-73-3)
- N-(pyridin-4-ylmethyl)pyridin-3-amine (CAS 227017-98-3)
- 1-Oxo Colterol (CAS 105644-17-5)
- 2-(2,3,4-Trifluorophenyl)acetonitrile (CAS 243666-13-9)
- 8-Bromo-6-chloroquinolin-4-ol (CAS 1388060-25-0)
- (4Z)-1-(4-Chlorophenyl)-4-{[(4-chlorophenyl)amino]methylidene}-3-ethoxy-4,5-dihydro-1H-pyrazol-5-one (CAS 338751-06-7)
- (R)-3-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(2,3-dichlorophenyl)propanoic acid (CAS 511272-38-1)
- 5-Methoxy-3-((methylsulfonyl)methyl)-1,3,4-thiadiazol-2(3H)-one (CAS 16967-89-8)
- (3S,4R)-Ethyl 1-methyl-4-phenylpyrrolidine-3-carboxylate (CAS 1354484-94-8)
- Insulin Degludec Impurity 15 (CAS CATO-C4X-215715)
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