2-[4-(5-Ethyl-1,2,4-oxadiazol-3-yl)-1,3-dioxo-1H,2H,3H,5H,6H,7H,8H,9H-pyrimido[1,6-a]azepin-2-yl]-N-[(thiophen-2-yl)methyl]acetamide CAS 1775353-96-2
| CAS No. | 1775353-96-2 |
| Molecular Formula | C20H23N5O4S |
| Molecular Weight | 429.49 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-[4-(5-Ethyl-1,2,4-oxadiazol-3-yl)-1,3-dioxo-1H,2H,3H,5H,6H,7H,8H,9H-pyrimido[1,6-a]azepin-2-yl]-N-[(thiophen-2-yl)methyl]acetamide.
CATO supplies 2-[4-(5-Ethyl-1,2,4-oxadiazol-3-yl)-1,3-dioxo-1H,2H,3H,5H,6H,7H,8H,9H-pyrimido[1,6-a]azepin-2-yl]-N-[(thiophen-2-yl)methyl]acetamide (CAS 1775353-96-2), a certified reference material (molecular formula C20H23N5O4S, MW 429.49 g/mol) for analytical method development and quality control.
The molecular framework of 2-[4-(5-Ethyl-1,2,4-oxadiazol-3-yl)-1,3-dioxo-1H,2H,3H,5H,6H,7H,8H,9H-pyrimido[1,6-a]azepin-2-yl]-N-[(thiophen-2-yl)methyl]acetamide (C20H23N5O4S) is characterized by a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C20H23N5O4S |
| Molecular Weight | 429.49 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1994 |
| Nitrogen Atoms | 5 |
| Sulfur Atoms | 1 |
Related Ethyl Standards
- 1-(8-(1,3,4-Oxadiazol-2-yl)-2,4-bis(trifluoromethyl)imidazo[1,2-a][1,8]naphthyridin-5-yl)-N,N-dimethylmethanamine (CAS 1431424-64-4)
- 2-[4-(5-Ethyl-1,2,4-oxadiazol-3-yl)-1,3-dioxo-1H,2H,3H,5H,6H,7H,8H,9H-pyrimido[1,6-a]azepin-2-yl]-N-(4-fluorophenyl)acetamide (CAS 1775338-08-3)
- 2-[4-(5-Ethyl-1,2,4-oxadiazol-3-yl)-1,3-dioxo-1H,2H,3H,5H,6H,7H,8H-pyrido[1,2-c]pyrimidin-2-yl]-N-(3-fluoro-4-methylphenyl)acetamide (CAS 1775502-61-8)
- 2-[4-(5-Ethyl-1,2,4-oxadiazol-3-yl)-1,3-dioxo-1H,2H,3H,5H,6H,7H,8H-pyrido[1,2-c]pyrimidin-2-yl]-N-[(4-fluorophenyl)methyl]acetamide (CAS 1775533-43-1)
- 2-[4-(5-Ethyl-1,2,4-oxadiazol-3-yl)-1,3-dioxo-1H,2H,3H,5H,6H,7H,8H,9H-pyrimido[1,6-a]azepin-2-yl]-N-(2-fluorophenyl)acetamide (CAS 1775554-40-9)
- 2-[4-(5-Ethyl-1,2,4-oxadiazol-3-yl)-1,3-dioxo-1H,2H,3H,5H,6H,7H,8H-pyrido[1,2-c]pyrimidin-2-yl]-N-(3-methoxyphenyl)acetamide (CAS 1775485-73-8)
- 2-[4-(5-Ethyl-1,2,4-oxadiazol-3-yl)-1,3-dioxo-1H,2H,3H,5H,6H,7H,8H-pyrido[1,2-c]pyrimidin-2-yl]-N-(2-methoxyphenyl)acetamide (CAS 1775541-81-5)
- 2-(5-Phenyl-1,3,4-oxadiazol-2-yl)dodecyl benzoate (CAS 56894-64-5)
Recommended Standards
- Diethyl ((1R)-quinolin-4-yl(5-vinylquinuclidin-2-yl)methyl)phosphoramidate (CAS 1354565-16-4)
- N-(4-Methylphenyl)-2-[3-oxo-8-(piperidine-1-sulfonyl)-2H,3H-[1,2,4]triazolo[4,3-a]pyridin-2-yl]acetamide (CAS 1779131-88-2)
- Diethyl ((1S)-quinolin-4-yl(5-vinylquinuclidin-2-yl)methyl)phosphoramidate (CAS 1354565-13-1)
- Methyl 6-hydroxy-5-(3-methoxy-2,4-dimethyl-6-(methylsulfonamido)phenyl)-2-naphthoate (CAS 1832514-22-3)
- 2-((1-(4-(Trifluoromethoxy)phenyl)-1H-pyrrol-2-yl)methylene)malononitrile (CAS 260788-89-4)
- 5-Bromo-1-(2-fluorobenzyl)-1H-pyrazole (CAS 1057383-75-1)
- 2-Chloro-N-(2-((2,3-dimethylphenyl)amino)-2-oxoethyl)acetamide (CAS 743456-90-8)
- 2-(2-Methyl-3-nitrophenyl)-1,3,4-oxadiazole (CAS 1092345-76-0)
- 5-Bromo-4-cyclopropyl-6-methoxypyrimidine (CAS 1649454-57-8)
- 4,4'-((2S,5S)-1-(4-(tert-Butyl)phenyl)pyrrolidine-2,5-diyl)dianiline, 97% (CAS 1258235-06-1)
- 7-ADCA Impurity 4 (CAS 27255-72-7)
- N-(6-Amino-1-(4-methoxyphenyl)-3-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)-3,5-dibutyl-4-hydroxybenzamide (CAS 176370-47-1)
- 4-Bromo-5-hydroxy-2-methyl-2H-pyridazin-3-one (CAS 64178-59-2)
- Tripeptide-10 citrulline (CAS 960531-53-7)
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