5-Methyl-N-(3-methylphenyl)-12-oxo-5H,5aH,6H,7H,8H,9H,10H,12H-azepino[2,1-b]quinazoline-3-carboxamide CAS 1775357-56-6
| CAS No. | 1775357-56-6 |
| Molecular Formula | C22H25N3O2 |
| Molecular Weight | 363.45 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 5-Methyl-N-(3-methylphenyl)-12-oxo-5H,5aH,6H,7H,8H,9H,10H,12H-azepino[2,1-b]quinazoline-3-carboxamide (C22H25N3O2) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
5-Methyl-N-(3-methylphenyl)-12-oxo-5H,5aH,6H,7H,8H,9H,10H,12H-azepino[2,1-b]quinazoline-3-carboxamide (CAS 1775357-56-6), molecular formula C22H25N3O2 and molecular weight 363.45 g/mol, is a CATO reference standard with documented purity and traceability.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C22H25N3O2 |
| Molecular Weight | 363.45 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1994 |
| Nitrogen Atoms | 3 |
Recommended Standards
- tert-Butyl (S)-2-((1R,2S)-3-(benzyloxy)-1-hydroxy-2-methyl-3-oxopropyl)pyrrolidine-1-carboxylate (CAS 173653-47-9)
- 5-Methyl-N-(4-methylphenyl)-12-oxo-5H,5aH,6H,7H,8H,9H,10H,12H-azepino[2,1-b]quinazoline-3-carboxamide (CAS 1775357-60-2)
- tert-Butyl (4-(benzyloxy)-8-methylnaphthalen-2-yl)carbamate (CAS 1662687-76-4)
- N-Benzyl-5-methyl-12-oxo-5H,5aH,6H,7H,8H,9H,10H,12H-azepino[2,1-b]quinazoline-3-carboxamide (CAS 1775357-93-1)
- 2-Cyano-N-cyclobutylacetamide (CAS 1064448-86-7)
- N1-β-D-Glucopyranosylamino-guanidine HCl (CAS 109853-81-8)
- 4-Ethyl-1H-pyrrole-2-carbaldehyde (CAS 187842-17-7)
- Erlotinib Impurity 19 (CAS CATO-C4X-106919)
- Quizalofop-P-tefuryl (CAS 200509-41-7)
- 3-Methoxy-4-(pyrrolidin-1-yl)benzonitrile (CAS 1393442-48-2)
- 3-Chloro-5-(2-fluoroethoxy)pyridazine (CAS 1346691-39-1)
- 1-Ethyl-8-fluoroquinolin-4(1H)-one (CAS 1211795-81-1)
- 1,2-Dichlorooctane (CAS 21948-46-9)
- Semaglutide impurity 86 (CAS CATO-C4X-222686)
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