1-(2-Chloro-4-fluorobenzoyl)-4-{[3-(4-fluorophenyl)-1,2,4-oxadiazol-5-yl]methyl}piperidine CAS 1775402-74-8
| CAS No. | 1775402-74-8 |
| Molecular Formula | C21H18ClF2N3O2 |
| Molecular Weight | 417.84 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
1-(2-Chloro-4-fluorobenzoyl)-4-{[3-(4-fluorophenyl)-1,2,4-oxadiazol-5-yl]methyl}piperidine (CAS 1775402-74-8), molecular formula C21H18ClF2N3O2 and molecular weight 417.84 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 1-(2-Chloro-4-fluorobenzoyl)-4-{[3-(4-fluorophenyl)-1,2,4-oxadiazol-5-yl]methyl}piperidine (C21H18ClF2N3O2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 13.0, corresponding to approximately 13 ring(s) or double-bond equivalent(s). With a molecular weight of 417.84 g/mol, it falls into the moderately-high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 1-(2-Chloro-4-fluorobenzoyl)-4-{[3-(4-fluorophenyl)-1,2,4-oxadiazol-5-yl]methyl}piperidine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C21H18ClF2N3O2 |
| Molecular Weight | 417.84 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1994 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
Related Chloro Standards
- 1-(2-Chloro-5-fluorobenzoyl)-4-{[3-(4-fluorophenyl)-1,2,4-oxadiazol-5-yl]methyl}piperidine (CAS 1775467-05-4)
- 6-Chloro-N2,N4-bis(2,4-dimethoxyphenyl)-1,3,5-triazine-2,4-diamine (CAS 333326-28-6)
- 6-Chloro-N2,N4-bis(3,4-dimethoxyphenyl)-1,3,5-triazine-2,4-diamine (CAS 374101-89-0)
- 3-(2-Chloro-6-fluorobenzyl)-1-(3,4-dimethoxyphenethyl)-4-hydroxypyridin-2(1H)-one (CAS 477856-19-2)
- 5-Chloro-2-methoxy-N-{4-methoxy-8-oxatricyclo[7.4.0.0^{2,7}]trideca-1(9),2(7),3,5,10,12-hexaen-5-yl}benzene-1-sulfonamide (CAS 861211-68-9)
- 1-Benzyl-3-chloro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-4-(trimethylsilyl)pyridin-2(1H)-one (CAS 1010101-15-1)
- 1-Benzyl-3-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-5-(trimethylsilyl)pyridin-2(1H)-one (CAS 1417647-26-7)
- (E)-1-(4-((3-chloro-5-(trifluoromethyl)pyridin-2-yl)oxy)phenyl)-3-(p-tolyl)prop-2-en-1-one (CAS 866039-14-7)
Recommended Standards
- tert-Butyl N-(2-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}ethyl)-N-methanesulfonylcarbamate (CAS 339105-16-7)
- Methyl 3-(N-(3-chloro-4-fluorophenyl)sulfamoyl)-4-fluorobenzo[b]thiophene-2-carboxylate (CAS 932464-84-1)
- Methyl 2-amino-4-(2-chloro-6-fluorophenyl)-5-oxo-4H,5H-thiochromeno[4,3-b]pyran-3-carboxylate (CAS 939894-16-3)
- 4-{3-[(4-chlorophenyl)thio]-2,5-dioxotetrahydro-1H-pyrrol-1-yl}-3-fluorobenzene-1-sulphonyl fluoride (CAS 284674-62-0)
- 1-(3,4-Dimethylbenzyl)-1H-pyrrole-3-carboxylic acid (CAS 1500889-67-7)
- 2-((5-Benzyl-1,3,4-oxadiazol-2-yl)thio)-N-(2,4-dimethylphenyl)acetamide (CAS 220598-05-0)
- 1-Bromo-3-(cyclopropylmethyl)-5-methylbenzene (CAS 1369877-39-3)
- 1-Isopropylpyrrolidin-2-one (CAS 3772-26-7)
- 5-Amino-5-deoxy-5-N-MMT-thymidine 3-CE phosphoramidite (CAS 194034-71-4)
- (3aR,4S,5R,6aS)-4-(((tert-Butyldimethylsilyl)oxy)methyl)-2-oxohexahydro-2H-cyclopenta[b]furan-5-yl benzoate (CAS 64982-34-9)
- 7-Bromo-2H-chromen-2-one (CAS 19063-56-0)
- 773877-46-6 9574AE C13H15N3O6S [[(1,3-Dimethyl-2,4-dioxo-1,2,3,4-tetrahydro-quinazolin-6-yl)sulfonyl](methyl)amino]acetic acid (CAS 773877-46-6)
- 6966-45-6 A836593 trisodium; (3Z)-3-[(E)-[4-[bis(oxidanidyl)amino]-6-oxidanylidene-cyclohexa-2,4-dien-1-ylidene]hydrazinylidene]-4-oxidanylidene-naphthalene-1-sulfonate; chromium(3+); 3-[(4-nitro-2-oxidanidyl-phenyl)diazenyl]-4-oxidanidyl-naphthalene-1-sulfonate trisodium; chromium(3+); (3Z)-3-[(E)-[4-(dioxidoamino)-6-oxo-1-cyclohexa-2,4-dienylidene]hydrazinylidene]-4-oxo-1-naphthalenesulfonate; 3-(4-nitro-2-oxidophenyl)azo-4-oxido-1-naphthalenesulfonate (CAS 6966-45-6)
- Semaglutide impurity 93 (CAS CATO-C4X-222693)
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