3-[1-(3,4-Difluorobenzoyl)piperidin-4-yl]-4-(4-methylphenyl)-4,5-dihydro-1H-1,2,4-triazol-5-one CAS 1775412-31-1
| CAS No. | 1775412-31-1 |
| Molecular Formula | C21H20F2N4O2 |
| Molecular Weight | 398.41 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 398.41 g/mol gives 3-[1-(3,4-Difluorobenzoyl)piperidin-4-yl]-4-(4-methylphenyl)-4,5-dihydro-1H-1,2,4-triazol-5-one distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
3-[1-(3,4-Difluorobenzoyl)piperidin-4-yl]-4-(4-methylphenyl)-4,5-dihydro-1H-1,2,4-triazol-5-one (CAS 1775412-31-1), molecular formula C21H20F2N4O2 and molecular weight 398.41 g/mol, is a CATO reference standard with documented purity and traceability.
Based on its molecular formula C21H20F2N4O2, 3-[1-(3,4-Difluorobenzoyl)piperidin-4-yl]-4-(4-methylphenyl)-4,5-dihydro-1H-1,2,4-triazol-5-one contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 398.41 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 3-[1-(3,4-Difluorobenzoyl)piperidin-4-yl]-4-(4-methylphenyl)-4,5-dihydro-1H-1,2,4-triazol-5-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C21H20F2N4O2 |
| Molecular Weight | 398.41 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1994 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
Related Difluorobenzoyl Standards
- 1-(2,5-Difluorobenzoyl)-4-{[3-(4-fluorophenyl)-1,2,4-oxadiazol-5-yl]methyl}piperidine (CAS 1775495-59-4)
- N-[(2,6-Difluorobenzoyl)oxy]-N-[(Z)-(3-nitro-4-piperidinophenyl)methylidene]amine (CAS 339019-80-6)
- 4-(2,6-Difluorobenzoyl)-N-(3-(trifluoromethyl)benzyl)-1H-pyrrole-2-carboxamide (CAS 439112-13-7)
- 4-(2,6-Difluorobenzoyl)-1-(2-fluorobenzyl)-3-methyl-3,4-dihydroquinoxalin-2(1H)-one (CAS 317833-46-8)
- 4-(2,6-Difluorobenzoyl)-1-(4-fluorobenzyl)-3-methyl-3,4-dihydroquinoxalin-2(1H)-one (CAS 317833-47-9)
- 3-[1-(2,6-Difluorobenzoyl)piperidin-4-yl]-4-[(4-methylphenyl)methyl]-4,5-dihydro-1H-1,2,4-triazol-5-one (CAS 1775397-13-1)
- 3-[1-(2,5-Difluorobenzoyl)piperidin-4-yl]-4-phenyl-4,5-dihydro-1H-1,2,4-triazol-5-one (CAS 1775382-43-8)
- 3-[1-(3,4-Difluorobenzoyl)piperidin-4-yl]-4-phenyl-4,5-dihydro-1H-1,2,4-triazol-5-one (CAS 1775382-66-5)
Recommended Standards
- 3,3,3',3'-Tetramethyl-5,5'-dinitro-2,2',3,3'-tetrahydro-1,1'-spirobi[indene]-6,6'-diol (CAS 158518-97-9)
- N-(3-((2-Fluorophenyl)amino)quinoxalin-2-yl)-1-methyl-1H-pyrazole-4-sulfonamide (CAS 1798530-41-2)
- 4,4′-[Methylenebis(4,1-phenyleneimino)]bis[4-oxobutanoic acid] (CAS 155267-38-2)
- (4-Nitrobenzyl)triphenylphosphonium (CAS 18583-39-6)
- 4-iso-Propylaniline-2,3,5,6-d4 (CAS 1219804-95-1)
- 2-(6-Oxo-1,6-dihydropyridazin-3-yl)-2-phenylacetonitrile (CAS 338753-08-5)
- 5-Methyl-1-((tetrahydro-2H-pyran-4-yl)methyl)-1H-pyrazole-4-carboxylic acid (CAS 1340093-64-2)
- ethyl 4-[(chlorosulfonyl)methyl]-4-fluorocyclohexane-1-carboxylate (CAS 1955498-99-3)
- N1-(2-Methoxybenzyl)-N2-(5-methylisoxazol-3-yl)oxalamide (CAS 899974-45-9)
- tert-Butyl 2-aminopiperidine-1-carboxylate (CAS 885954-09-6)
- 4-Pentafluoroethyloxy-butyl-ammonium chloride (CAS 1286743-94-9)
- S-(4-Nitrophenyl)-L-cysteine (CAS 55288-30-7)
- (3-Aminopiperidin-1-yl)(cyclopropyl)methanone hydrochloride (CAS 1158742-26-7)
- Acetyl decapeptide-3 (CAS 935288-50-9)
Why CATO?
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