N-(3-Chloro-4-fluorophenyl)-5-methyl-12-oxo-5H,5aH,6H,7H,8H,9H,10H,12H-azepino[2,1-b]quinazoline-3-carboxamide CAS 1775442-36-8
| CAS No. | 1775442-36-8 |
| Molecular Formula | C21H21ClFN3O2 |
| Molecular Weight | 401.86 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies N-(3-Chloro-4-fluorophenyl)-5-methyl-12-oxo-5H,5aH,6H,7H,8H,9H,10H,12H-azepino[2,1-b]quinazoline-3-carboxamide (CAS 1775442-36-8), a certified reference material (molecular formula C21H21ClFN3O2, MW 401.86 g/mol) for analytical method development and quality control.
Structurally, N-(3-Chloro-4-fluorophenyl)-5-methyl-12-oxo-5H,5aH,6H,7H,8H,9H,10H,12H-azepino[2,1-b]quinazoline-3-carboxamide (C21H21ClFN3O2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 12.0, corresponding to approximately 12 ring(s) or double-bond equivalent(s). With a molecular weight of 401.86 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), N-(3-Chloro-4-fluorophenyl)-5-methyl-12-oxo-5H,5aH,6H,7H,8H,9H,10H,12H-azepino[2,1-b]quinazoline-3-carboxamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C21H21ClFN3O2 |
| Molecular Weight | 401.86 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1994 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
Related N Standards
- Methyl 4-((4'-chloro-[1,1'-biphenyl])-4-sulfonamido)benzoate (CAS 1182284-29-2)
- N-(3-Chloro-4-fluorophenyl)-5-ethyl-11-oxo-5H,5aH,6H,7H,8H,9H,11H-pyrido[2,1-b]quinazoline-3-carboxamide (CAS 1574577-04-0)
- 3-[Benzyl-(2-chloro-phenyl)-sulfamoyl]-benzoic acid (CAS 750613-52-6)
- 4-(((4'-Chloro-[1,1'-biphenyl])-4-sulfonamido)methyl)benzoic acid (CAS 885269-34-1)
- 4-(2-Chloro-4-methoxyphenyl)-2-morpholino-5-(4H-1,2,4-triazol-3-yl)thiophene-3-carbonitrile (CAS 1202041-57-3)
- (2E)-3-{4-[(2-chloro-6-fluorophenyl)methoxy]phenyl}-N-[(thiophen-2-yl)methyl]prop-2-enamide (CAS 477870-70-5)
- 2-(3-(((4-Chloro-5-cyano-6-(thiophen-2-yl)pyrimidin-2-yl)thio)methyl)phenyl)acetic acid (CAS 2428519-99-5)
- (2E)-3-{4-[(2-chloro-6-fluorophenyl)methoxy]phenyl}-N-cycloheptylprop-2-enamide (CAS 477870-71-6)
Recommended Standards
- 1-[(4-Chlorophenyl)sulfanyl]-4-[(4-methoxyphenoxy)methyl]-2-nitrobenzene (CAS 477869-42-4)
- 2,2-Diacetyl-3-(4-chlorophenyl)-1-(phenylsulfonyl)cyclopropane-1-carbonitrile (CAS 860611-37-6)
- 4-((2-Chlorophenyl)diazenyl)-3-hydroxy-N-phenyl-2-naphthamide (CAS 6410-26-0)
- 3-(Benzyl-phenyl-sulfamoyl)-4-chloro-benzoic acid (CAS 733762-51-1)
- Pyrrolo[1,2-a]thieno[2,3-e]pyrazin-6-amine (CAS 106723-67-5)
- Ethyl 5-(bis(2-hydroxyethyl)amino)-1H-indole-3-carboxylate (CAS 7150-82-5)
- 3-(Oxazol-4-yl)benzonitrile (CAS 620971-49-5)
- N1-cyclopropyl-N1-isopropyl-N2-(thietan-3-yl)ethane-1,2-diamine (CAS 1878399-12-2)
- (E)-3-(2-(((4-methylbenzyl)oxy)imino)ethyl)-4-phenylthiophene-2,5-dicarbonitrile (CAS 343372-53-2)
- 8-methoxy-3-methyl-4-oxo-1,4-dihydroquinoline-2-carboxylic acid (CAS 55895-58-4)
- Bromisoval Impurity 2 (CAS 2274-08-0)
- Butane-1,3-diyl dioctanoate (CAS 4554-00-1)
- 2-(4-Acetyl-3-nitrophenyl)acetic acid (CAS 2007919-23-3)
- C-Peptide (Proinsulin) (CAS 59112-80-0)
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