N-(3-Methoxyphenyl)-2-[4-(5-methyl-1,2,4-oxadiazol-3-yl)-1,3-dioxo-1H,2H,3H,5H,6H,7H,8H,9H-pyrimido[1,6-a]azepin-2-yl]acetamide CAS 1775444-40-0
| CAS No. | 1775444-40-0 |
| Molecular Formula | C21H23N5O5 |
| Molecular Weight | 425.44 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of N-(3-Methoxyphenyl)-2-[4-(5-methyl-1,2,4-oxadiazol-3-yl)-1,3-dioxo-1H,2H,3H,5H,6H,7H,8H,9H-pyrimido[1,6-a]azepin-2-yl]acetamide is closely related to a flavonoid core, an amide group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
N-(3-Methoxyphenyl)-2-[4-(5-methyl-1,2,4-oxadiazol-3-yl)-1,3-dioxo-1H,2H,3H,5H,6H,7H,8H,9H-pyrimido[1,6-a]azepin-2-yl]acetamide (CAS 1775444-40-0), molecular formula C21H23N5O5 and molecular weight 425.44 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of N-(3-Methoxyphenyl)-2-[4-(5-methyl-1,2,4-oxadiazol-3-yl)-1,3-dioxo-1H,2H,3H,5H,6H,7H,8H,9H-pyrimido[1,6-a]azepin-2-yl]acetamide (C21H23N5O5) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures N-(3-Methoxyphenyl)-2-[4-(5-methyl-1,2,4-oxadiazol-3-yl)-1,3-dioxo-1H,2H,3H,5H,6H,7H,8H,9H-pyrimido[1,6-a]azepin-2-yl]acetamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C21H23N5O5 |
| Molecular Weight | 425.44 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1994 |
| Nitrogen Atoms | 5 |
Related N Standards
- N-[(4-Methoxyphenyl)methyl]-2-[4-(5-methyl-1,2,4-oxadiazol-3-yl)-1,3-dioxo-1H,2H,3H,5H,6H,7H,8H-pyrido[1,2-c]pyrimidin-2-yl]acetamide (CAS 1775308-43-4)
- N-(2-Methoxyphenyl)-2-[4-(5-methyl-1,2,4-oxadiazol-3-yl)-1,3-dioxo-1H,2H,3H,5H,6H,7H,8H,9H-pyrimido[1,6-a]azepin-2-yl]acetamide (CAS 1775354-09-0)
- 2-(4-Methoxyphenyl)-5-(3,4,5-trimethoxybenzylidene)thiazolo[3,2-b][1,2,4]triazol-6(5H)-one (CAS 606952-70-9)
- (3E)-3-[2-(4-Methoxyphenyl)hydrazin-1-ylidene]-1-{[3-(trifluoromethyl)phenyl]methyl}-2,3-dihydro-1H-indol-2-one (CAS 303984-93-2)
- 2-(4-Methoxyphenyl)-2-oxoethyl 3-methyl-2-(p-tolyl)quinoline-4-carboxylate (CAS 355826-66-3)
- 2-((3-(4-Methoxyphenyl)-4-oxo-3,4,6,7-tetrahydrothieno[3,2-d]pyrimidin-2-yl)thio)-N-phenylacetamide (CAS 850915-58-1)
- 9,10-Bis(4-methoxyphenyl)-2-chloroanthracene (CAS 110904-87-5)
- (4,5-Bis(4-methoxyphenyl)thiazol-2-yl)(4-methylpiperazin-1-yl)methanone hydrochloride (CAS 130717-51-0)
Recommended Standards
- N-(4-Ethoxyphenyl)-2-[4-(5-methyl-1,2,4-oxadiazol-3-yl)-1,3-dioxo-1H,2H,3H,5H,6H,7H,8H-pyrido[1,2-c]pyrimidin-2-yl]acetamide (CAS 1775407-05-0)
- N-(2-Ethoxyphenyl)-2-[4-(5-methyl-1,2,4-oxadiazol-3-yl)-1,3-dioxo-1H,2H,3H,5H,6H,7H,8H-pyrido[1,2-c]pyrimidin-2-yl]acetamide (CAS 1775485-25-0)
- 2-[4-(5-Ethyl-1,2,4-oxadiazol-3-yl)-1,3-dioxo-1H,2H,3H,5H,6H,7H,8H-pyrido[1,2-c]pyrimidin-2-yl]-N-(3-methoxyphenyl)acetamide (CAS 1775485-73-8)
- 2-[4-(5-Ethyl-1,2,4-oxadiazol-3-yl)-1,3-dioxo-1H,2H,3H,5H,6H,7H,8H-pyrido[1,2-c]pyrimidin-2-yl]-N-(2-methoxyphenyl)acetamide (CAS 1775541-81-5)
- 2,2,2-trifluoro-1-(5-methylfuran-2-yl)ethan-1-amine hydrochloride (CAS 1909337-90-1)
- (6-Chloro-5-cyclopropoxypyridin-3-yl)methanamine (CAS 1243471-71-7)
- 4-Methyl-1-(o-tolyl)pentane-1,3-dione (CAS 1341560-73-3)
- 4-Bromo-N-(2-fluorobenzyl)benzamide (CAS 895366-03-7)
- 3-Ethylnonane (CAS 17302-11-3)
- 2-Bromo-5-chloro-4-methylpyrimidine (CAS 1936719-98-0)
- 2-Chloro-4-(trifluoromethyl)oxazole (CAS 1060816-15-0)
- 4-Chloro-2-iodo-1-(phenylsulfonyl)-5-azaindole (CAS 1227270-34-9)
- 1-[(2-bromoethyl)sulfanyl]-2,4-difluorobenzene (CAS 1097824-30-0)
- Semaglutide impurity 71 (CAS CATO-C4X-222671)
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