3-[4-(4-Fluorophenyl)piperazine-1-carbonyl]-5-methyl-5H,5aH,6H,7H,8H,9H,10H,12H-azepino[2,1-b]quinazolin-12-one CAS 1775471-99-2
| CAS No. | 1775471-99-2 |
| Molecular Formula | C25H29FN4O2 |
| Molecular Weight | 436.52 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures 3-[4-(4-Fluorophenyl)piperazine-1-carbonyl]-5-methyl-5H,5aH,6H,7H,8H,9H,10H,12H-azepino[2,1-b]quinazolin-12-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
3-[4-(4-Fluorophenyl)piperazine-1-carbonyl]-5-methyl-5H,5aH,6H,7H,8H,9H,10H,12H-azepino[2,1-b]quinazolin-12-one (CAS 1775471-99-2) is a high-purity analytical reference standard with the molecular formula C25H29FN4O2 and a molecular weight of 436.52 g/mol.
The molecular framework of 3-[4-(4-Fluorophenyl)piperazine-1-carbonyl]-5-methyl-5H,5aH,6H,7H,8H,9H,10H,12H-azepino[2,1-b]quinazolin-12-one (C25H29FN4O2) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C25H29FN4O2 |
| Molecular Weight | 436.52 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1994 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
Related Fluorophenyl Standards
- 5-Ethyl-3-[4-(4-fluorophenyl)piperazine-1-carbonyl]-5H,5aH,6H,7H,8H,9H,11H-pyrido[2,1-b]quinazolin-11-one (CAS 1574596-49-8)
- 4-[(4-Fluorophenyl)sulfanyl]-5-(4-methylbenzenesulfonyl)-2-phenylpyrimidine (CAS 478247-29-9)
- (4-(4-Fluorophenyl)-1H-pyrrol-2-yl)(3-((3-(thiophen-3-yl)-1,2,4-oxadiazol-5-yl)methyl)piperidin-1-yl)methanone (CAS 1705210-29-2)
- (2Z)-2-[(4-Fluorophenyl)methylidene]-7-(4-methoxyphenoxy)-3-phenyl-2,3-dihydro-1H-inden-1-one (CAS 337921-52-5)
- 6-((4-Fluorophenyl)amino)-2,3-dimethylquinoxaline-5,8-dione (CAS 14334-06-6)
- N-(2-Fluorophenyl)-4-(2-{[(2-fluorophenyl)carbamothioyl]amino}ethyl)piperazine-1-carbothioamide (CAS 454651-99-1)
- 2-((4-Benzyl-5-(2-fluorophenyl)-4H-1,2,4-triazol-3-yl)thio)-N-(2-cyano-3-methylbutan-2-yl)acetamide (CAS 764699-96-9)
- 2-(3-(4-Fluorophenyl)-6-oxopyridazin-1(6H)-yl)-N-(2-(trifluoromethoxy)benzyl)propanamide (CAS 1226454-06-3)
Recommended Standards
- 3-[1-(4-tert-Butylbenzoyl)piperidin-4-yl]-4-[(4-fluorophenyl)methyl]-4,5-dihydro-1H-1,2,4-triazol-5-one (CAS 1775542-06-7)
- (3-Amino-4-(4-methoxyphenyl)-6-phenylthieno[2,3-b]pyridin-2-yl)(phenyl)methanone (CAS 126888-13-9)
- 4-(4-Methoxyphenyl)-2-((2-oxo-2-phenylethyl)thio)-6-phenylnicotinonitrile (CAS 189132-48-7)
- 5-(5-(((4-Isobutylphenyl)sulfonyl)methyl)furan-2-yl)-3-(m-tolyl)-1,2,4-oxadiazole (CAS 1251569-00-2)
- (3Z)-6-Methyl-3-[(2-phenylhydrazin-1-yl)methylidene]-3,4-dihydro-2H-pyran-2,4-dione (CAS 1164466-47-0)
- 1-(4-Ethoxyphenyl)-5-thioxopyrrolidin-2-one (CAS 100192-41-4)
- 4-(5,5-Dimethyl-1,3-dioxan-2-yl)piperidine oxalate (CAS 423768-60-9)
- (R)-3-((tert-Butoxycarbonyl)amino)-3-(4-fluorophenyl)propanoic acid (CAS 479064-94-3)
- 1-Acetyl-1,2-dihydro-3H-pyrrolo[2,3-b]pyridin-3-one (CAS 155818-89-6)
- 2-Propenoic acid, 2-methyl-, 1,1'-[1,2-ethanediylbis(oxy-2,1-ethanediyl)] ester, polymer with butyl 2-propenoate and methyl 2-methyl-2-propenoate (CAS 56938-23-9)
- (2-(2-Methyl-1H-imidazol-1-yl)phenyl)methanol (CAS 914349-47-6)
- Chloroprocaine Impurity 11 HCl (CAS 1049696-00-5)
- 5-(2-(Methylamino)pyridin-4-yl)-1,3,4-thiadiazol-2-amine (CAS 1240521-58-7)
- Fragment-[9-31]-Semaglutide (CAS CATO-C4X-2226181)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com