4-(Chloromethyl)-1-methyl-1,2-dihydropyridin-2-one CAS 177550-41-3
| CAS No. | 177550-41-3 |
| Molecular Formula | C7H8ClNO |
| Molecular Weight | 157.60 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
4-(Chloromethyl)-1-methyl-1,2-dihydropyridin-2-one (CAS 177550-41-3) is a high-purity analytical reference standard with the molecular formula C7H8ClNO and a molecular weight of 157.60 g/mol.
The molecular framework of 4-(Chloromethyl)-1-methyl-1,2-dihydropyridin-2-one (C7H8ClNO) is characterized by an amide group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO manufactures 4-(Chloromethyl)-1-methyl-1,2-dihydropyridin-2-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C7H8ClNO |
| Molecular Weight | 157.60 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2007 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
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Recommended Standards
- 2-(6-Chloropyridin-2-yl)ethan-1-ol (CAS 174666-23-0)
- 3-Chloro-2-ethoxypyridine (CAS 177743-06-5)
- 2-Chloro-1-(pyridin-4-yl)ethan-1-ol (CAS 174615-70-4)
- 2-Amino-3-chloro-5-methylphenol (CAS 1780449-40-2)
- n-(2-Methyl-3-oxo-3,4-dihydro-2h-benzo[b][1,4]oxazin-6-yl)butyramide (CAS 942835-71-4)
- 5-Bromo-3-hydroxy-4-methylpyridine (CAS 351458-21-4)
- 4-Bromo-2-chloro-6-(difluoromethyl)nicotinaldehyde (CAS 1805034-16-5)
- N-(2-Chloro-6-methylphenyl)formamide (CAS 10113-37-8)
- N-(1-(thiophen-3-yl)ethyl)thietan-3-amine (CAS 1855797-95-3)
- 2-Methylbenzeneselenol (CAS 37773-21-0)
- 1,3-Dimethyl-2-phenylnaphthalene (CAS 119264-82-3)
- 2-(2-(2-Chloro-5-fluorophenoxy)ethyl)-1,3-dioxane (CAS 1443330-38-8)
- n-Isopropyl-5-methoxypentan-1-amine (CAS 1281550-90-0)
- Tirzepatide Impurity 47 (CAS CATO-C4X-324047)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com