3-[1-(3-Fluoro-4-methylbenzoyl)piperidin-4-yl]-4-[(4-methylphenyl)methyl]-4,5-dihydro-1H-1,2,4-triazol-5-one CAS 1775506-32-5
| CAS No. | 1775506-32-5 |
| Molecular Formula | C23H25FN4O2 |
| Molecular Weight | 408.47 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 3-[1-(3-Fluoro-4-methylbenzoyl)piperidin-4-yl]-4-[(4-methylphenyl)methyl]-4,5-dihydro-1H-1,2,4-triazol-5-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
3-[1-(3-Fluoro-4-methylbenzoyl)piperidin-4-yl]-4-[(4-methylphenyl)methyl]-4,5-dihydro-1H-1,2,4-triazol-5-one (CAS 1775506-32-5) is a high-purity analytical reference standard with the molecular formula C23H25FN4O2 and a molecular weight of 408.47 g/mol.
3-[1-(3-Fluoro-4-methylbenzoyl)piperidin-4-yl]-4-[(4-methylphenyl)methyl]-4,5-dihydro-1H-1,2,4-triazol-5-one (C23H25FN4O2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C23H25FN4O2 |
| Molecular Weight | 408.47 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1994 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
Related Fluoro Standards
- Ethyl 6-(((5-fluoro-2-hydroxyphenyl)(phenyl)methyl)amino)-1,3a-dihydropyrazolo[1,5-a]pyrimidine-3-carboxylate (CAS 1951445-02-5)
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- N-(4-Fluoro-2-methylphenyl)-2-[5-(morpholine-4-sulfonyl)-2-oxo-1,2-dihydropyridin-1-yl]acetamide (CAS 1251698-44-8)
- 1-(4-Fluoro-5-methyl-2-nitrophenyl)-4-(4-methoxybenzenesulfonyl)piperazine (CAS 1262222-56-9)
- 4-(3-Fluoro-5-((4-(2-methyl-1h-imidazol-1-yl)benzyl)oxy)phenyl)tetrahydro-2h-pyran-4-carboxylic acid (CAS 179420-54-3)
- 5-((3-(3-Fluoro-4-methylphenyl)-1-phenyl-1H-pyrazol-4-yl)methylene)-3-methyl-2-thioxothiazolidin-4-one (CAS 623936-10-7)
- 2-Fluoro-N-(1-(1-(p-tolyl)-1H-1,2,3-triazole-4-carbonyl)piperidin-4-yl)benzamide (CAS 1251624-31-3)
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Recommended Standards
- 3-{1-[2-(3-fluorophenyl)acetyl]piperidin-4-yl}-4-[(4-methylphenyl)methyl]-4,5-dihydro-1H-1,2,4-triazol-5-one (CAS 1775384-85-4)
- Methyl (2R)-2-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}-3-(1,3-thiazol-4-yl)propanoate (CAS 1820574-14-8)
- Fmoc-N-Me-Ala(4-Thz)-OH (CAS 1446478-22-3)
- 2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-2-(2-ethylthiazol-4-yl)acetic acid (CAS 1869395-97-0)
- 166888-26-2 2-(Bromomethyl)-5-(phthalimidomethyl)thiophene 2-[[5-(Bromomethyl)-2-thienyl]methyl]-1H-isoindole-1,3(2H)-dione (CAS 166888-26-2)
- 1-(4-chlorophenyl)-5-ethyl-2-sulfanylidene-1,3-diazinane-4,6-dione (CAS 1308650-31-8)
- 2-(2-Oxabicyclo[3.1.0]Hexan-6-yl)acetic acid (CAS 1936603-87-0)
- Atrasentan Impurity 65 (CAS 403614-23-3)
- 1-Bromo-2-(2-fluorophenoxy)benzene (CAS 1445322-62-2)
- 3-[2-(Morpholine-4-carbonyl)-phenoxy]-piperidine-1-carboxylic acid tert-butyl ester (CAS 1146080-58-1)
- 2,3,4-Trifluoro-5-formylbenzoic acid, 97% (CAS 926629-49-4)
- 2,5-Dimethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol (CAS 1487353-52-5)
- Pantoprazole Impurity 3 (CAS 957470-58-5)
- Semaglutide Impurity 192 (CAS CATO-C4X-2226192)
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