(Z)-(1,2-difluorovinyl)trimethylsilane CAS 17757-16-3
| CAS No. | 17757-16-3 |
| Molecular Formula | C5H10F2Si |
| Molecular Weight | 136.22 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of (Z)-(1,2-difluorovinyl)trimethylsilane (C5H10F2Si) is characterized by fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO supplies (Z)-(1,2-difluorovinyl)trimethylsilane (CAS 17757-16-3), a certified reference material (molecular formula C5H10F2Si, MW 136.22 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C5H10F2Si |
| Molecular Weight | 136.22 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | Stable under recommended storage conditions |
| Degree of Unsaturation (DBE) | 0.0 |
| CAS Registry Year (est.) | 1962 |
| Halogen Content | F-containing |
Related Z Standards
- (2,2-Difluorovinyl)benzene (CAS 405-42-5)
- 2-(2,2-Difluorovinyl)Pyridine (CAS 108615-85-6)
- 4-(2,2-Difluorovinyl)Pyridine (CAS 344902-30-3)
- 4-(2,2-Difluorovinyl)pyrrolidin-2-one (CAS 854141-89-2)
- 1-(1,2-Difluorovinyl)cyclopentan-1-ol (CAS 408524-39-0)
- 1-(2,2-Difluorovinyl)cyclopropan-1-amine (CAS 2688115-09-3)
- 1-[(E)-1,2-Difluorovinyl]-4-Fluorobenzene (CAS 316173-80-5)
- 2-(2,2-Difluorovinyl)bicyclo[2.2.1]heptane (CAS 123455-94-7)
Recommended Standards
- ((2-Aminoethyl)imino)dimethyl-lambda6-sulfanone (CAS 1622050-37-6)
- (2-Aminoethyl)(methyl)(methylimino)-lambda6-sulfanone (CAS 1936175-88-0)
- Methyl 2-Methylpropane-2-sulfinate (CAS 52056-71-0)
- Methyl(phenyl)silanone (CAS 4543-12-8)
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- 3,5-Dibromo-4-hydroxycinnamicacid (CAS 56926-78-4)
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- 3-Hydroxy-2,3-dihydro-1H-inden-1-one (CAS 26976-59-0)
- 1-Benzyl 3-ethyl 5-fluoropiperidine-1,3-dicarboxylate (CAS 1823995-53-4)
- (4R)-4-phenyl-3-(1,2-propadienyl)-2-Oxazolidinone (CAS 256382-50-0)
- 2-Thioxo-2,3-dihydro-1H-imidazole-4-carbaldehyde (CAS 13953-95-2)
- 3-Methanesulfonylcyclohexan-1-ol (CAS 1342041-13-7)
- 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)naphthalen-2-ol (CAS 2043962-01-0)
- Semaglutide impurity 273 (CAS CATO-C4X-2226273)
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