2-(4-Ethoxyphenyl)-3-hydroxy-4H-chromen-4-one CAS 177587-97-2
| CAS No. | 177587-97-2 |
| Molecular Formula | C17H14O4 |
| Molecular Weight | 282.29 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-(4-Ethoxyphenyl)-3-hydroxy-4H-chromen-4-one.
2-(4-Ethoxyphenyl)-3-hydroxy-4H-chromen-4-one (CAS 177587-97-2), molecular formula C17H14O4 and molecular weight 282.29 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 2-(4-Ethoxyphenyl)-3-hydroxy-4H-chromen-4-one (C17H14O4) is characterized by a flavonoid core, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C17H14O4 |
| Molecular Weight | 282.29 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2007 |
Related Ethoxyphenyl Standards
- (2E)-3-(2-Ethoxyphenyl)-1-(2-methoxyphenyl)prop-2-en-1-one (CAS 1175867-24-9)
- (2E)-3-(4-Ethoxyphenyl)-1-(2-methoxyphenyl)prop-2-en-1-one (CAS 1181788-49-7)
- (2E)-1-(4-Ethoxyphenyl)-3-(4-methoxyphenyl)prop-2-en-1-one (CAS 158575-01-0)
- (2E)-1-(4-Ethoxyphenyl)-3-(2-methoxyphenyl)prop-2-en-1-one (CAS 1801686-30-5)
- (2E)-1-(4-Ethoxyphenyl)-3-(3-methoxyphenyl)prop-2-en-1-one (CAS 6002-50-2)
- (2E)-3-(2-Ethoxyphenyl)-1-(3-methoxyphenyl)prop-2-en-1-one (CAS 358656-49-2)
- (2E)-3-(2-Ethoxyphenyl)-1-(4-methoxyphenyl)prop-2-en-1-one (CAS 358656-32-3)
- (2E)-3-(4-Ethoxyphenyl)-1-(3-methoxyphenyl)prop-2-en-1-one (CAS 358656-50-5)
Recommended Standards
- Methyl 3-((tert-butoxycarbonyl)amino)-2-methoxyisonicotinate (CAS 175965-50-1)
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- 5-(4-Methoxyphenyl)-5-phenylimidazolidine-2,4-dione (CAS 17816-50-1)
- 1-Benzyl-4-(3-fluorobenzyl)piperidine (CAS 771456-84-9)
- (R)-1-Boc-piperazine-2-ethanol Hydrochloride (CAS 947275-74-3)
- 6-(Dimethylamino)pyridine-2-carboximidamide (CAS 1341182-11-3)
- 3-Bromo-2-(bromomethyl)-1,1,1-trifluoropropane (CAS 1263377-32-7)
- (2R,3R,4S,5S)-2-methoxytetrahydro-2H-pyran-3,4,5-triol (CAS 3945-28-6)
- 2-((1H-Imidazol-4-yl)methyl)-5-ethyl-4-methylthiazole (CAS 713487-38-8)
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- 2-(Furan-2-yl)-5,6-dimethyl-1H-benzo[d]imidazole (CAS 91954-83-5)
- Des-Ile17-Tirzepatide (CAS CATO-CPTD788956)
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