(4-Formyl-2-(trifluoromethyl)phenyl)boronic acid CAS 1777807-55-2
| CAS No. | 1777807-55-2 |
| Molecular Formula | C8H6BF3O3 |
| Molecular Weight | 217.94 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including (4-Formyl-2-(trifluoromethyl)phenyl)boronic acid.
(4-Formyl-2-(trifluoromethyl)phenyl)boronic acid (CAS 1777807-55-2) is a high-purity analytical reference standard with the molecular formula C8H6BF3O3 and a molecular weight of 217.94 g/mol.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system, (4-Formyl-2-(trifluoromethyl)phenyl)boronic acid is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 217.94 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H6BF3O3 |
| Molecular Weight | 217.94 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1994 |
| Halogen Content | F-containing |
Related Formyl Standards
- (4-Formyl-3-(trifluoromethyl)phenyl)boronic acid (CAS 1072944-24-1)
- (2-Formyl-5-(trifluoromethyl)phenyl)boronic acid (CAS 1204580-94-8)
- (2-Formyl-4-(trifluoromethyl)phenyl)boronic acid (CAS 1217501-35-3)
- (2-Formyl-6-(trifluoromethyl)phenyl)boronic acid (CAS 1451392-93-0)
- (3-Formyl-5-(trifluoromethyl)phenyl)boronic acid (CAS 1451393-24-0)
- 5-Formyl-2-(trifluoromethyl)phenylboronic acid (CAS 2377606-70-5)
- N-Formyl 2-bromo-4-fluoroaniline (CAS 1495962-01-0)
- 4-Formyl-3-(trifluoromethyl)benzoic acid (CAS 1289083-41-5)
Recommended Standards
- (4-((1,2,2-Trifluorovinyl)oxy)phenyl)boronic acid (CAS 213701-14-5)
- 2,5-Dinitrothiophene-3-boronic acid (CAS 2377608-57-4)
- 2,5-Difluoro-4-(methoxymethoxy)phenylboronic acid (CAS 1451392-29-2)
- (5-Nitroisoquinolin-8-yl)boronic acid (CAS 1620751-71-4)
- Methyl 2-(4-bromo-2-chloro-5-methylphenyl)acetate (CAS 1428761-26-5)
- 5-Methyl-12-oxo-N-(3,4,5-trimethoxyphenyl)-5H,5aH,6H,7H,8H,9H,10H,12H-azepino[2,1-b]quinazoline-3-carboxamide (CAS 1775442-93-7)
- 5-(2-Methylbutyl)-3-(2-methylprop-1-en-1-yl)-2H-pyrrole-2,4(3H)-dione (CAS 496941-95-8)
- ((S)-2-Amino-4-(tert-butoxy)-4-oxobutanoyl)-L-proline (CAS 64642-65-5)
- Methyl 2-nitro-5-(piperidin-1-yl)benzoate (CAS 773071-23-1)
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- (2S,4S)-1-(tert-butoxycarbonyl)-4-(4-ethoxyphenoxy)pyrrolidine-2-carboxylic acid (CAS 1354486-38-6)
- 4-chlorophenyl 2-(3,5-dimethyl-1H-pyrazol-1-yl)-4-phenyl-1,3-thiazol-5-yl sulfone 955976-35-9 KS-000038GL (CAS 955976-35-9)
- Semaglutide impurity 98 (CAS CATO-C4X-222698)
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