3,3-Difluoro-1-(3-fluoro-2-(trifluoromethyl)-phenyl)pyrrolidine CAS 1779132-29-4
| CAS No. | 1779132-29-4 |
| Molecular Formula | C11H9F6N |
| Molecular Weight | 269.19 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 3,3-Difluoro-1-(3-fluoro-2-(trifluoromethyl)-phenyl)pyrrolidine (C11H9F6N) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO supplies 3,3-Difluoro-1-(3-fluoro-2-(trifluoromethyl)-phenyl)pyrrolidine (CAS 1779132-29-4), a certified reference material (molecular formula C11H9F6N, MW 269.19 g/mol) for analytical method development and quality control.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 3,3-Difluoro-1-(3-fluoro-2-(trifluoromethyl)-phenyl)pyrrolidine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H9F6N |
| Molecular Weight | 269.19 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1994 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Difluoro Standards
- 3,3-Difluoro-1-(2-fluoro-6-(trifluoromethyl)-phenyl)pyrrolidine (CAS 1707605-07-9)
- 3,3-Difluoro-1-(4-fluoro-2-(trifluoromethyl)-phenyl)pyrrolidine 1779132-20-5 (CAS 1779132-20-5)
- Ethyl difluoro[3-(trifluoromethyl)-pyridin-2-yl]acetate (CAS 1216499-24-9)
- Ethyl 2,2-difluoro-2-(5-(trifluoromethyl)pyridin-2-yl)acetate (CAS 1216700-64-9)
- 2,2-Difluoro-N-methyl-2-(3-(trifluoromethyl)phenoxy)acetamide (CAS 339010-84-3)
- 2,6-Difluoro-N-methoxy-N-methyl-4-(trifluoromethyl)benzamide (CAS 1980040-18-3)
- benzyl 3,3-Difluoro-4-oxopiperidine-1-carboxylate (CAS 1283720-88-6)
- Ethyl 5,8-difluoro-4-thioxo-1,4-dihydroquinoline-3-carboxylate (CAS 1315347-04-6)
Recommended Standards
- (1R,2S)-2-(3,5-bis(trifluoromethyl)phenyl)cyclopropan-1-amine (CAS 705250-99-3)
- (2-Chlorobenzyl)(4-chlorophenyl)sulfane (CAS 735327-53-4)
- (3-Chlorobenzyl)(3-chlorophenyl)sulfane (CAS 1443327-71-6)
- (3-Chlorobenzyl)(4-chlorophenyl)sulfane (CAS 393126-24-4)
- N-(3,6-Dimethylbenzo[d]thiazol-2(3H)-ylidene)pentanamide (CAS 391229-83-7)
- 5-(4-(4-Methoxyphenyl)piperazine-1-carbonyl)pyrrolidin-2-one (CAS 110957-23-8)
- tert-Butyl n-[cyano(2-methoxyphenyl)methyl]carbamate (CAS 774225-46-6)
- 3A-fluorooctahydrocyclopenta[c]pyrrole (CAS 2167854-60-4)
- 4-(Methylsulfonyl)-N-phenylpiperidine-1-carboxamide (CAS 1787917-17-2)
- 4-Chloro-3-phenyl-1H-pyrrolo[2,3-b]pyridine (CAS 1261744-30-2)
- 4-[(2,6-dimethylmorpholin-4-yl)methyl]benzoic acid (CAS 926198-81-4)
- 4-chloropyrrolo[2,1-f][1,2,4]triazine-7-carbonitrile (CAS 1356017-80-5)
- 5-(8-(Methylamino)imidazo[1,2-a]pyrazin-3-yl)pyridin-2(1H)-one (CAS 825630-48-6)
- Semaglutide impurity 75 (CAS CATO-C4X-222675)
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