2-Amino-5-fluoro-3-nitrobenzoic acid CAS 177960-62-2
| CAS No. | 177960-62-2 |
| Molecular Formula | C7H5FN2O4 |
| Molecular Weight | 200.12 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 2-Amino-5-fluoro-3-nitrobenzoic acid (C7H5FN2O4) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
2-Amino-5-fluoro-3-nitrobenzoic acid (CAS 177960-62-2), molecular formula C7H5FN2O4 and molecular weight 200.12 g/mol, is a CATO reference standard with documented purity and traceability.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 2-Amino-5-fluoro-3-nitrobenzoic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H5FN2O4 |
| Molecular Weight | 200.12 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2007 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Amino Standards
- 2-Amino-3-fluoro-5-nitrobenzoic acid (CAS 101336-14-5)
- 2-Amino-4-fluoro-5-nitrobenzoic acid (CAS 1194097-41-0)
- 2-Amino-5-fluoro-4-nitrobenzoic acid (CAS 174566-51-9)
- 2-Amino-6-fluoro-3-nitrobenzoic acid (CAS 910123-26-1)
- 4-Amino-2-fluoro-5-nitro-benzoic acid (CAS 807327-07-7)
- 4-Amino-3-fluoro-5-nitrobenzoic acid (CAS 803700-08-5)
- 5-Amino-4-fluoro-2-nitrobenzoic acid (CAS 53994-61-9)
- 6-Amino-2,2-difluoro-2H-benzo[b][1,4]oxazin-3(4H)-one (CAS 575473-95-9)
Recommended Standards
- 3-(Difluoromethyl)-4-fluoro-6-formylpicolinonitrile (CAS 1804493-86-4)
- 6,7,8-Trifluoroquinazolin-4(3H)-one (CAS 1564582-39-3)
- 3-(Difluoromethyl)-5-fluoro-6-formylpicolinonitrile (CAS 1804493-97-7)
- Methyl 6-fluoro-5-nitronicotinate (CAS 1379331-55-1)
- 5-Bromo-2-(4-isobutylpiperazin-1-yl)pyrimidine (CAS 1252362-50-7)
- Chlorazifop Propargyl Ester (CAS 72280-52-5)
- Desosamine (CAS 5779-39-5)
- (2E)-3-(2-Fluorophenyl)-1-(2-methylphenyl)prop-2-en-1-one (CAS 1354942-42-9)
- (S)-2-m-Tolyl-propionic acid (CAS 601472-22-4)
- Tetramethyl Orthosilicate (CAS 681-84-5)
- 4-(Benzyloxy)-3-oxobutanenitrile (CAS 118602-96-3)
- 4-(3-Chlorobenzyl)-3-cyano-N-(thiazol-2-yl)benzenesulfonamide (CAS 1799439-21-6)
- 3-(4-Nitrophenyl)isothiazolo[5,4-d]pyrimidin-4-amine (CAS 605660-65-9)
- Semaglutide impurity 57 (CAS 2773558-06-6)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com