Ziprasidone impurity 53 CAS 177985-31-8
| CAS No. | 177985-31-8 |
| Molecular Formula | C8H8ClNO2 |
| Molecular Weight | 185.61 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a process- or degradation-related impurity, Ziprasidone impurity 53 (CAS 177985-31-8, C8H8ClNO2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Ziprasidone impurity 53 (C8H8ClNO2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO manufactures Ziprasidone impurity 53 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H8ClNO2 |
| Molecular Weight | 185.61 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2007 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Ziprasidone Standards
- Ziprasidone Impurity 60 (CAS 2166666-15-3)
- Ziprasidone Impurity 21 (CAS 118306-76-6)
- Ziprasidone Impurity 79 (CAS 661463-77-0)
- Ziprasidone Impurity 20 (CAS 65435-04-3)
- Ziprasidone Impurity 76 (CAS CATO-C4X-124076)
- Ziprasidone Impurity 31 (CAS 510703-85-2)
- Ziprasidone Impurity 23 (CAS CATO-C4X-124023)
- Ziprasidone EP Impurity A (CAS 87691-87-0)
Recommended Standards
- Methyl 2-(chloromethyl)nicotinate (CAS 177785-14-7)
- Methyl 6-chloro-5-methylpicolinate (CAS 178421-22-2)
- 4-Chloro-1,6-dimethyl-2-oxo-1,2-dihydropyridine-3-carbaldehyde (CAS 176683-50-4)
- 5-Amino-4-chloro-2-methylbenzoic acid (CAS 1784397-04-1)
- Luliconazole Impurity 2 (CAS 1240249-76-6)
- Anastrozole EP Impurity H (CAS 120511-72-0)
- Betamethasone Unknown Impurity 3 (CAS CATO-CPS-2303001)
- Ethyl 1-(5-((4-chlorophenyl)thio)-4-phenylthiazol-2-yl)-5-(trifluoromethyl)-1H-pyrazole-4-carboxylate (CAS 956755-68-3)
- 2-(2-Ethylphenyl)-4-oxo-1,4-dihydroquinoline-6-carboxylic acid (CAS 90034-28-9)
- 5-amino-1-methyl-1,2-dihydro-3H-pyrazol-3-one (CAS 54167-77-0)
- 3-Chloro-N-{3-cyano-4-[(2-methylphenyl)sulfanyl]phenyl}benzamide (CAS 306980-78-9)
- N-(2-Hydroxyethyl)-3-oxobutanamide (CAS 24309-97-5)
- 2-(Aminomethyl)-6-(difluoromethyl)-5-methyl-3-nitropyridine (CAS 1805559-32-3)
- Semaglutide Sodium Salt (CAS CATO-C4X-222620)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com