2,4,6-Trichloro-5-methylpyrimidine CAS 1780-36-5
| CAS No. | 1780-36-5 |
| Molecular Formula | C5H3Cl3N2 |
| Molecular Weight | 197.45 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
2,4,6-Trichloro-5-methylpyrimidine (CAS 1780-36-5), molecular formula C5H3Cl3N2 and molecular weight 197.45 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrile group, chlorine substitution, 2,4,6-Trichloro-5-methylpyrimidine is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 197.45 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO manufactures 2,4,6-Trichloro-5-methylpyrimidine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C5H3Cl3N2 |
| Molecular Weight | 197.45 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Trichloro Standards
- 4,5,6-Trichloro-2-methylpyrimidine (CAS 1780-28-5)
- 2,4,5-Trichloro-6-methylpyrimidine (CAS 6554-69-4)
- 3,4,5-Trichloro-6-methylpyridazine (CAS 66572-23-4)
- 3,4,6-Trichloro-5-methylpyridazine (CAS 499235-55-1)
- 3,5,6-Trichloro-2-Pyridinol (CAS 6515-38-4)
- 3,4,5-Trichloro-2-methyl-pyridine (CAS 1187932-77-9)
- 2,3,5-Trichloro-4-methylpyridine (CAS 53939-29-0)
- 2,3,6-Trichloro-5-methylpyridine (CAS 58584-95-5)
Recommended Standards
- 2-chloro-4-(dichloromethyl)pyrimidine (CAS 1803566-44-0)
- 2,4,5-Trichloropyridin-3-amine (CAS 173435-47-7)
- 3,5-Dichloro-2-(chloromethyl)pyrazine (CAS 1824441-19-1)
- 3,5,6-Trichloropyridin-2-amine (CAS 1378670-79-1)
- Z-Gly-Gly-Nva-OH (C-1790.0001) (CAS 63623-61-0)
- 6-Amino-5-iodonicotinaldehyde (CAS 1289104-23-9)
- rac-cis-1-Deshydroxy Rasagiline (CAS 1429220-15-4)
- (2-(4-FLUOROPHENYL)-2-OXOETHYL)TRIPHENYLPHOSPHONIUM BROMIDE (CAS 120302-61-6)
- 3-Ethynyl-5-methylpyridin-2-amine (CAS 863479-77-0)
- 2-Iodo-6-(trifluoromethyl)benzaldehyde (CAS 1261612-24-1)
- (1-(Tetrahydro-2H-pyran-4-yl)pyrrolidin-3-yl)methanol (CAS 1342113-95-4)
- (E)-ethyl 3-(2-chloro-4-(ethylamino)pyrimidin-5-yl)acrylate (CAS 2449269-93-4)
- ACrylate-peg6-t-butyl ester (CAS 1807537-32-1)
- α Bag Cell Peptide (1-9) (CAS 87549-52-8)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com