2,4,6-Trichloro-5-isopropylpyrimidine CAS 1780-42-3

Purity 97%+In StockPharmaceutical Standards
CAS No.1780-42-3
Molecular FormulaC7H7Cl3N2
Molecular Weight225.50 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2,4,6-Trichloro-5-isopropylpyrimidine CAS 1780-42-3 chemical structure

Description

The occurrence of 2,4,6-Trichloro-5-isopropylpyrimidine is closely related to a nitrile group, chlorine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

CATO supplies 2,4,6-Trichloro-5-isopropylpyrimidine (CAS 1780-42-3), a certified reference material (molecular formula C7H7Cl3N2, MW 225.50 g/mol) for analytical method development and quality control.

The molecular framework of 2,4,6-Trichloro-5-isopropylpyrimidine (C7H7Cl3N2) is characterized by a nitrile group, chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 2,4,6-Trichloro-5-isopropylpyrimidine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC7H7Cl3N2
Molecular Weight225.50 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)4.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1957
Halogen ContentCl-containing
Nitrogen Atoms2

Related Trichloro Standards

Recommended Standards

Why CATO?