2-(4,4-difluorocyclohexyl)ethanamine;hydrochloride CAS 1780237-68-4
| CAS No. | 1780237-68-4 |
| Molecular Formula | C8H15F2N |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 2-(4,4-difluorocyclohexyl)ethanamine;hydrochloride is closely related to fluorine/chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
2-(4,4-difluorocyclohexyl)ethanamine;hydrochloride (CAS 1780237-68-4) is a high-purity analytical reference standard with the molecular formula C8H15F2NHCl and a molecular weight of 199.67 g/mol.
Structurally, 2-(4,4-difluorocyclohexyl)ethanamine;hydrochloride (C8H15F2NHCl) contains fluorine/chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 0.0, corresponding to approximately 0 ring(s) or double-bond equivalent(s). With a molecular weight of 199.67 g/mol, it falls into the medium-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H15F2N HCl |
| Molecular Weight | 199.67 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 0.0 |
| CAS Registry Year (est.) | 1994 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related difluorocyclohexyl Standards
- Ethyl 2-(2,2-difluorocyclohexyl)acetate (CAS 1035559-58-0)
- (4,4-Difluorocyclohexyl)hydrazine (CAS 1082745-52-5)
- 2-(2,2-Difluorocyclohexyl)ethan-1-ol (CAS 1190973-69-3)
- (4,4-Difluorocyclohexyl)hydrazine 2,2,2-trifluoroacetate (CAS 1214910-81-2)
- 1-(4,4-Difluorocyclohexyl)ethan-1-one (CAS 121629-16-1)
- 2-(3,3-Difluorocyclohexyl)-4-phenylpyridine (CAS 1241505-00-9)
- 2-(3,3-Difluorocyclohexyl)-1-methyl-4-phenylpiperidine (CAS 1241505-02-1)
- Benzyl 2-(3,3-difluorocyclohexyl)-4-phenylpiperidine-1-carboxylate (CAS 1241505-07-6)
Recommended Standards
- 2-(5-Chloro-3-fluoropyridin-2-yl)acetonitrile (CAS 1227572-25-9)
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- 2-[4-(aminomethyl)phenyl]-1,2-thiazolidine-1,1-dione (CAS 1016529-85-3)
- Ethyl (4-(N-(5-ethyl-1,3,4-thiadiazol-2-yl)sulfamoyl)phenyl)carbamate (CAS 92110-38-8)
- 3-(2,5-Dimethyl-1H-pyrrol-1-yl)-3-(4-fluorophenyl)propanoic acid (CAS 866040-75-7)
- 2-Bromopyridine-3-acetic Acid (CAS 1227578-15-5)
- 3-((4-Fluorobenzyl)thio)-4-methyl-5-(thiophen-2-yl)-4H-1,2,4-triazole (CAS 329699-48-1)
- 2,5-Dichloro-6-cyclopropylnicotinonitrile (CAS 1135283-17-8)
- Semaglutide impurity 85 (CAS CATO-C4X-222685)
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