[1-(difluoromethyl)cyclobutyl]methanol CAS 1780499-30-0
| CAS No. | 1780499-30-0 |
| Molecular Formula | C6H10F2O |
| Molecular Weight | 136.14 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), [1-(difluoromethyl)cyclobutyl]methanol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
[1-(difluoromethyl)cyclobutyl]methanol (CAS 1780499-30-0), molecular formula C6H10F2O and molecular weight 136.14 g/mol, is a CATO reference standard with documented purity and traceability.
[1-(difluoromethyl)cyclobutyl]methanol (C6H10F2O) contains a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C6H10F2O |
| Molecular Weight | 136.14 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Stable under recommended storage conditions |
| Degree of Unsaturation (DBE) | 1.0 |
| CAS Registry Year (est.) | 1994 |
| Halogen Content | F-containing |
Related difluoromethyl Standards
- 2-(Difluoromethyl)piperazine (CAS 111759-98-9)
- (3-(Difluoromethyl)azetidin-3-yl)methanamine (CAS 1779935-18-0)
- (2-(Difluoromethyl)cyclobutyl)methanol (CAS 1780163-99-6)
- 4-(Difluoromethyl)tetrahydro-2H-pyran (CAS 1820618-46-9)
- (2R)-2-(difluoromethyl)piperazine (CAS 817554-43-1)
- (S)-2-(Difluoromethyl)piperazine (CAS 2165613-39-6)
- 1-(Difluoromethyl)cyclopropanecarboxylic Acid (CAS 1314397-71-1)
- 2-(difluoromethyl)cyclopropanecarboxylic acid (CAS 1314960-20-7)
Recommended Standards
- (1-(1,1-Difluoroethyl)cyclopropyl)methanol (CAS 1780526-08-0)
- 1-(3,3-difluorocyclobutyl)ethan-1-ol (CAS 1784303-38-3)
- 3-(2,2-Difluoroethyl)cyclobutan-1-ol (CAS 1779935-03-3)
- (2,2-Difluorocyclopentyl)methanol (CAS 1554145-36-6)
- 1-(Bromomethyl)-1-ethylcyclohexane (CAS 1498749-61-3)
- Cyclohexyl 2-isopropyl-5-methyl-4-nitrobenzoate (CAS 4277-14-9)
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- Procaterol Impurity 6 (CAS CATO-C4X-18106)
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- 4-Ethyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzonitrile (CAS 1448869-99-5)
- Biotinyl-S6 Phosphate Acceptor Peptide trifluoroacetate salt (CAS 1815618-12-2)
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