8-Bromo-1,1-difluoro-1,2,3,4-tetrahydronaphthalene CAS 1780625-21-9
| CAS No. | 1780625-21-9 |
| Molecular Formula | C10H9BrF2 |
| Molecular Weight | 247.08 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 8-Bromo-1,1-difluoro-1,2,3,4-tetrahydronaphthalene.
CATO supplies 8-Bromo-1,1-difluoro-1,2,3,4-tetrahydronaphthalene (CAS 1780625-21-9), a certified reference material (molecular formula C10H9BrF2, MW 247.08 g/mol) for analytical method development and quality control.
8-Bromo-1,1-difluoro-1,2,3,4-tetrahydronaphthalene (C10H9BrF2) contains fluorine/bromine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 8-Bromo-1,1-difluoro-1,2,3,4-tetrahydronaphthalene meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H9BrF2 |
| Molecular Weight | 247.08 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1994 |
| Halogen Content | F/Br-containing |
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