6-Bromo-3-methyl-1H-indole-2-carboxylic acid CAS 1780710-91-9
| CAS No. | 1780710-91-9 |
| Molecular Formula | C10H8BrNO2 |
| Molecular Weight | 254.08 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 6-Bromo-3-methyl-1H-indole-2-carboxylic acid (CAS 1780710-91-9), a certified reference material (molecular formula C10H8BrNO2, MW 254.08 g/mol) for analytical method development and quality control.
6-Bromo-3-methyl-1H-indole-2-carboxylic acid (C10H8BrNO2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, bromine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 6-Bromo-3-methyl-1H-indole-2-carboxylic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H8BrNO2 |
| Molecular Weight | 254.08 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1994 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 1 |
Related Bromo Standards
- 2-(7-Bromo-1H-indol-2-yl)acetic acid (CAS 1018591-46-2)
- 2-(6-Bromo-1H-indol-2-yl)acetic acid (CAS 1018635-71-6)
- 2-Bromo-6-(furan-2-ylmethoxy)pyridine (CAS 1065484-89-0)
- 1-Acetyl-5-bromo-2H-indol-3-one (CAS 106698-07-1)
- Methyl 3-Bromo-4-(cyanomethyl)benzoate (CAS 1069114-89-1)
- 3-(5-Bromo-2-methoxyphenyl)-3-oxopropanenitrile (CAS 1071398-50-9)
- Methyl 6-bromo-4-indolecarboxylate (CAS 107650-22-6)
- 5-Bromo-2-methyl-1H-indole-3-carboxylic acid (CAS 1082572-35-7)
Recommended Standards
- 3-(2-Bromo-5-methoxyphenyl)-3-oxopropanenitrile (CAS 175136-65-9)
- 2-(aminomethyl)-7-bromo-4H-pyrido[1,2-a]pyrimidin-4-one (CAS 1780782-32-2)
- 6-Bromo-3-hydroxy-1-methylquinolin-2(1H)-one (CAS 172604-64-7)
- 4-Bromo-1-methyl-1H-indole-6-carboxylic acid (CAS 1782217-26-8)
- Ethyl 2-(4-(2-chloro-N-methylacetamido)phenyl)-3,3,3-trifluoro-2-hydroxypropanoate (CAS 340029-62-1)
- 3-(2-Thienyl)-1H-indole-2-carboxylic acid (CAS 1220027-01-9)
- 7-Chloro-N-(pyridin-2-ylmethyl)quinolin-4-amine (CAS 854355-54-7)
- Rhenium heptasulfide, 99% 5GR (CAS 12038-67-4)
- 2-(2-Chloro-4-formylphenoxy)-n-(2-fluorophenyl)acetamide (CAS 717891-68-4)
- 1-(2-Fluoro-4-nitrophenyl)pyrrolidine (CAS 385380-74-5)
- 4-(Tert-butyl)-N-((2-chlorophenyl)carbamothioyl)benzamide (CAS 364628-24-0)
- Vildagliptin Impurity 81 (CAS CATO-C4X-110081)
- 1,3-Dihydroxy-5-methoxy-9H-xanthen-9-one (CAS 6563-47-9)
- Semaglutide Impurity 10 (CAS CATO-C4X-222610)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com