7-Bromo-6-fluoro-2-methyl-1,2,3,4-tetrahydroisoquinoline CAS 1780751-74-7
| CAS No. | 1780751-74-7 |
| Molecular Formula | C10H11BrFN |
| Molecular Weight | 244.10 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 7-Bromo-6-fluoro-2-methyl-1,2,3,4-tetrahydroisoquinoline (CAS 1780751-74-7), a certified reference material (molecular formula C10H11BrFN, MW 244.10 g/mol) for analytical method development and quality control.
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/bromine substitution, 7-Bromo-6-fluoro-2-methyl-1,2,3,4-tetrahydroisoquinoline is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 244.10 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 7-Bromo-6-fluoro-2-methyl-1,2,3,4-tetrahydroisoquinoline under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H11BrFN |
| Molecular Weight | 244.10 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1994 |
| Halogen Content | F/Br-containing |
| Nitrogen Atoms | 1 |
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Recommended Standards
- 8-Bromo-5-fluoro-2-methyl-1,2,3,4-tetrahydroisoquinoline (CAS 1780432-47-4)
- 1-(4-Bromophenyl)-3-fluorocyclobutan-1-amine (CAS 1781152-58-6)
- 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrolo[2,3-c]pyridine (CAS 1573171-42-2)
- (1r,3r)-3-(3-Bromo-4-fluorophenyl)cyclobutan-1-amine (CAS 1807936-49-7)
- Benzyl ((1-(2-hydroxyethyl)piperidin-4-yl)methyl)(isopropyl)carbamate (CAS 1353973-04-2)
- 2-((3-Nitrobenzyl)thio)ethan-1-amine (CAS 144907-41-5)
- 3-(3-Methyl-1H-pyrazol-1-yl)propanamide (CAS 301165-48-0)
- 1-(Benzyloxy)-4-bromo-5-ethyl-2-fluorobenzene (CAS 1825308-38-0)
- 2-((4,5-Dihydro-1H-imidazol-2-yl)thio)-1-phenylethan-1-one hydrobromide (CAS 32188-94-6)
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- 5-Bromo-N2-isopropylpyridine-2,3-diamine (CAS 1215916-59-8)
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- Nelonicline, >98% (HPLC) (CAS 1026134-63-3)
- ([D2]Gly4)-Cholecystokinin Octapeptide (sulfated) ammonium salt (CAS 1926163-74-7)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com