1-Bromo-4-fluoro-5-methoxy-2-methylbenzene CAS 1780981-61-4
| CAS No. | 1780981-61-4 |
| Molecular Formula | C8H8BrFO |
| Molecular Weight | 219.05 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 219.05 g/mol gives 1-Bromo-4-fluoro-5-methoxy-2-methylbenzene distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
1-Bromo-4-fluoro-5-methoxy-2-methylbenzene (CAS 1780981-61-4), molecular formula C8H8BrFO and molecular weight 219.05 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a hydroxyl group, an ether linkage, fluorine/bromine substitution, an aromatic ring system, 1-Bromo-4-fluoro-5-methoxy-2-methylbenzene is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 219.05 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 1-Bromo-4-fluoro-5-methoxy-2-methylbenzene meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H8BrFO |
| Molecular Weight | 219.05 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1994 |
| Halogen Content | F/Br-containing |
Related Bromo Standards
- (2-Bromo-5-fluorobenzyl)hydrazine (CAS 1016529-00-2)
- (5-Bromo-2-fluorobenzyl)hydrazine (CAS 1016699-41-4)
- (1s)-1-(4-Bromo-2-fluorophenyl)ethan-1-ol (CAS 1026088-11-8)
- 1-Bromo-4-ethoxy-2-fluorobenzene (CAS 107713-66-6)
- (R)-2-Bromo-1-(4-fluorophenyl)ethanol (CAS 1097211-38-5)
- 4-bromo-1-ethoxy-2-fluorobenzene (CAS 115467-08-8)
- (S)-2-Bromo-1-(3-fluorophenyl)ethan-1-ol (CAS 1176484-68-6)
- 5-Bromo-2-fluoro-3-methylbenzyl alcohol (CAS 1197944-22-1)
Recommended Standards
- 2-Bromo-1-fluoro-3-methoxy-4-methylbenzene (CAS 1780793-97-6)
- 2-(4-Bromophenyl)-2-fluoroethan-1-ol (CAS 1781801-90-8)
- 2-Bromo-1-(fluoromethyl)-3-methoxybenzene (CAS 1780793-90-9)
- 1-Bromo-4-fluoro-2-methoxy-3-methylbenzene (CAS 1783385-83-0)
- 4-Nitro-2-(4-vinylphenyl)isoindoline-1,3-dione (CAS 89014-95-9)
- Ethyl 3-formyl-2-methylindolizine-7-carboxylate (CAS 59195-46-9)
- 5-(Furan-2-yl)pyrimidine-2,4-diol (CAS 55625-98-4)
- 4-(tert-Butyl)benzene-1-carbonyl isothiocyanate (CAS 680214-97-5)
- 4-Difluoromethyl-2,6-dimethylanisole (CAS 1803873-52-0)
- 4-((4-(Dimethylamino)phenyl)(4-(dimethyliminio)cyclohexa-2,5-dien-1-ylidene)methyl)-3-hydroxy-7-sulfonaphthalene-2-sulfonate (CAS 25317-10-6)
- 4-[(4-bromo-1h-pyrazol-1-yl)methyl]aniline (CAS 512809-49-3)
- rel-(1R,5S,6s)-3-azabicyclo[3.1.0]hexane-6-carboxylic acid;hydrochloride (CAS 2200003-25-2)
- [2-(Mercapto-κS)acetato(2-)-κO]calcium (CAS 37457-75-3)
- Semaglutide Impurity 162 (x TFA Salt) (CAS CATO-C4X-2226162)
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