7-(trifluoromethyl)quinazoline-4-carboxylic acid CAS 1781377-74-9

Purity 97%+In StockPharmaceutical Standards
CAS No.1781377-74-9
Molecular FormulaC10H15F3N2O2
Molecular Weight252.23 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

7-(trifluoromethyl)quinazoline-4-carboxylic acid CAS 1781377-74-9 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 252.23 g/mol gives 7-(trifluoromethyl)quinazoline-4-carboxylic acid distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

CATO supplies 7-(trifluoromethyl)quinazoline-4-carboxylic acid (CAS 1781377-74-9), a certified reference material (molecular formula C10H15F3N2O2, MW 252.23 g/mol) for analytical method development and quality control.

Based on its molecular formula C10H15F3N2O2, 7-(trifluoromethyl)quinazoline-4-carboxylic acid contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 252.23 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 7-(trifluoromethyl)quinazoline-4-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC10H15F3N2O2
Molecular Weight252.23 g/mol
AppearanceWhite to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)3.0
UV AbsorptionUV-absorbing
CAS Registry Year (est.)1994
Halogen ContentF-containing
Nitrogen Atoms2

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