3-(3,5-Dimethoxyphenyl)-2,2-dimethylpropanoic acid CAS 1781655-77-3
| CAS No. | 1781655-77-3 |
| Molecular Formula | C13H18O4 |
| Molecular Weight | 238.28 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 3-(3,5-Dimethoxyphenyl)-2,2-dimethylpropanoic acid.
3-(3,5-Dimethoxyphenyl)-2,2-dimethylpropanoic acid (CAS 1781655-77-3), molecular formula C13H18O4 and molecular weight 238.28 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 3-(3,5-Dimethoxyphenyl)-2,2-dimethylpropanoic acid (C13H18O4) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C13H18O4 |
| Molecular Weight | 238.28 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1994 |
Related Dimethoxyphenyl Standards
- 2-(2,5-Dimethoxyphenyl)-3-methylbutanoic acid (CAS 1082507-47-8)
- 5-(3,4-Dimethoxyphenyl)pentanoic acid (CAS 1145-15-9)
- 2-(2,4-Dimethoxyphenyl)-3-methylbutanoic acid (CAS 1226259-74-0)
- 2-(3,4-Dimethoxyphenyl)-3-methylbutanoic acid (CAS 92157-19-2)
- 3-(3,4-Dimethoxyphenyl)-3-methylbutanoic acid (CAS 33214-44-7)
- 5-(2,3-Dimethoxyphenyl)pentanoic acid (CAS 54130-93-7)
- Ethyl 3-(3,4-dimethoxyphenyl)propionate (CAS 5462-13-5)
- Ethyl 3-(3,5-dimethoxyphenyl)propanoate (CAS 54901-09-6)
Recommended Standards
- N-((3R,4R)-4-fluoropyrrolidin-3-yl)-3-(methylsulfonyl)propanamide (CAS 1776113-95-1)
- 2-Methoxy-10,11-dihydro-5H-dibenzo[a,d][7]annulen-5-one (CAS 17910-72-4)
- 2'-Hydroxy -5'- methyl chalcone (CAS 1775-98-0)
- 3-Methoxy Dibenzosuberone (CAS 17910-76-8)
- 3-((6-Fluoro-8-methylquinolin-4-yl)amino)benzoic acid (CAS 1315373-74-0)
- tert-Butyl 3-(4-amino-2-fluorophenyl)propanoate (CAS 865138-41-6)
- N-(Quinolin-4-ylmethyl)ethanamine (CAS 680590-98-1)
- 1-Cyanocyclopentane 4254-02-8 Cyanocyclopentane Cyclopentanecarbonitrile Cyclopentanenitrile Cyclopentyl Nitrile Cyclopentyl cyanide (CAS 4254-02-8)
- (R)-5-((tert-Butoxycarbonyl)amino)-3-methylpentanoic acid (CAS 2550997-53-8)
- 5-Cyclopropyl-2-methylphenol (CAS 1421253-25-9)
- 2-(2,2-Dimethyl-1-oxopropyl)propanedinitrile (CAS 141458-79-9)
- 6-methylpiperidin-2-one (CAS 4775-98-8)
- Methyl 2-bromo-5-hydroxybenzoate (CAS 154607-00-8)
- Serpent Peptide 2AcOH (CAS 823202-99-9(free base))
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