1-(3-Chloro-2-fluoro-6-methoxyphenyl)ethanone CAS 1781675-28-2
| CAS No. | 1781675-28-2 |
| Molecular Formula | C9H8ClFO2 |
| Molecular Weight | 202.61 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Structurally, 1-(3-Chloro-2-fluoro-6-methoxyphenyl)ethanone (C9H8ClFO2) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 5.0, corresponding to approximately 5 ring(s) or double-bond equivalent(s). With a molecular weight of 202.61 g/mol, it falls into the medium-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
1-(3-Chloro-2-fluoro-6-methoxyphenyl)ethanone (CAS 1781675-28-2) is a high-purity analytical reference standard with the molecular formula C9H8ClFO2 and a molecular weight of 202.61 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 1-(3-Chloro-2-fluoro-6-methoxyphenyl)ethanone under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C9H8ClFO2 |
| Molecular Weight | 202.61 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1994 |
| Halogen Content | F/Cl-containing |
Related Chloro Standards
- 2-(2-Chloro-4-fluoro-5-methylphenyl)acetic acid (CAS 1000522-29-1)
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Recommended Standards
- 1-(2-Chloro-6-fluoro-3-methoxyphenyl)ethanone (CAS 1780699-75-3)
- 1-(6-Chloro-2-fluoro-3-methoxyphenyl)ethanone (CAS 1785596-93-1)
- 6-Chloro-5-hydroxy-2H-1,3-benzoxathiol-2-one (CAS 17631-05-9)
- Methyl 2-chloro-5-fluoro-3-methylbenzoate (CAS 1805112-73-5)
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- 3-[(2-(Benzyloxycarbonyl)aminoacetyl)amino]-2,4,6-triiodoisophthalic Acid (CAS 1796931-77-5)
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