2-(Diphenylphosphino)-1-naphthoic acid CAS 178176-80-2
| CAS No. | 178176-80-2 |
| Molecular Formula | C23H17O2P |
| Molecular Weight | 356.35 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
2-(Diphenylphosphino)-1-naphthoic acid (CAS 178176-80-2) is a high-purity analytical reference standard with the molecular formula C23H17O2P and a molecular weight of 356.35 g/mol.
The molecular framework of 2-(Diphenylphosphino)-1-naphthoic acid (C23H17O2P) is characterized by a steroid core, organophosphorus functionality, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO manufactures 2-(Diphenylphosphino)-1-naphthoic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C23H17O2P |
| Molecular Weight | 356.35 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 15.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2007 |
Related Diphenylphosphino Standards
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- 2-(Diphenylphosphino)benzenesulfonic acid (CAS 111864-25-6)
- 2-(Diphenylphosphino)-N,N-diethylbenzamide (CAS 143024-49-1)
Recommended Standards
- 1-((3A'R,4'R,6'R,6a'S)-6'-(fluoromethyl)-6'-(hydroxymethyl)-3a'-methyltetrahydrospiro[cyclopentane-1,2'-furo[3,4-d][1,3]dioxol]-4'-yl)pyrimidine-2,4(1H,3H)-dione (CAS 1643585-09-4)
- 2-(((Benzyloxy)carbonyl)amino)-3-(5-fluoro-1h-indol-3-yl)propanoic acid (CAS 1881-79-4)
- 2-((4-(2-(2-Fluorophenoxy)acetamido)but-2-yn-1-yl)oxy)benzamide (CAS 1421508-12-4)
- (11bR)-8,9,10,11,12,13,14,15-Octahydro-4-hydroxy-4-oxide-dinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepin (CAS 297752-25-1)
- 1-(2-Chloro-5-Fluoro-6-Methylaminopyridin-3-yl-2-(2-Dimethylaminoethoxy)Ethanol Hydrochloride (CAS 142934-88-1)
- 3-(4-Fluorobenzoyl)-4-methylpyridine (CAS 158978-22-4)
- 2-Chloroquinoline-3-carbonitrile (CAS 95104-21-5)
- 2-(4-(3-Fluorophenyl)-1h-imidazol-2-yl)piperidine hydrochloride (CAS 1803585-19-4)
- 2,5-Dimethyl-3-(3-methoxyphenyl)propiophenone (CAS 898774-78-2)
- 5-(Piperidin-2-yl)-3-(p-tolyl)-1,2,4-oxadiazole hydrochloride (CAS 1036556-56-5)
- 3,4,5-Trichlorobiphenyl-2′,3′,4′,5′,6′-d5 (CAS 93952-22-8)
- 2-Imino-5-((1-phenyl-3-(4-propoxyphenyl)-1H-pyrazol-4-yl)methylene)thiazolidin-4-one (CAS 381706-15-6)
- (3-((4-(3-Chlorophenyl)piperazin-1-yl)sulfonyl)thiophen-2-yl)(3,5-dimethyl-1H-pyrazol-1-yl)methanone (CAS 1207007-62-2)
- (9-D-Asp) Semaglutide X Sodium salt (CAS CATO-CPTD788617)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com