Methyl 5-amino-4-chloro-1-methyl-1H-pyrazole-3-carboxylate CAS 1781890-07-0
| CAS No. | 1781890-07-0 |
| Molecular Formula | C6H8ClN3O2 |
| Molecular Weight | 189.60 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 189.60 g/mol gives Methyl 5-amino-4-chloro-1-methyl-1H-pyrazole-3-carboxylate distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Methyl 5-amino-4-chloro-1-methyl-1H-pyrazole-3-carboxylate (CAS 1781890-07-0), molecular formula C6H8ClN3O2 and molecular weight 189.60 g/mol, is a CATO reference standard with documented purity and traceability.
Methyl 5-amino-4-chloro-1-methyl-1H-pyrazole-3-carboxylate (C6H8ClN3O2) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C6H8ClN3O2 |
| Molecular Weight | 189.60 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1994 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Methyl Standards
- 2-(3-Amino-4-chloro-1h-pyrazol-1-yl)propanoic acid (CAS 1006455-66-8)
- 3-(3-Amino-4-chloro-1h-pyrazol-1-yl)propanoic acid (CAS 1006455-70-4)
- (S)-2-Amino-3-(5-chloro-1H-imidazol-4-yl)propanoic acid (CAS 102974-88-9)
- (S)-2-Amino-3-(2-chloro-1H-imidazol-4-yl)propanoic acid (CAS 126663-37-4)
- 2-Amino-3-(5-chlorofuran-2-yl)propanoic acid (CAS 1270323-57-3)
- Methyl 2-(3-amino-4-chloro-1h-pyrazol-1-yl)acetate (CAS 1339160-83-6)
- 2-((5-Amino-6-chloropyrimidin-4-yl)oxy)ethan-1-ol (CAS 1342614-21-4)
- (3R)-3-amino-3-(3-chlorofuran-2-yl)propanoic acid (CAS 1366296-45-8)
Recommended Standards
- 8-Chloroquinoxaline-6-carbonitrile (CAS 1706445-52-4)
- Methyl 3-amino-4-chloro-1-methyl-1H-pyrazole-5-carboxylate (CAS 1784410-90-7)
- 6-chloro-5-nitro-pyridine-3-carbonitrile (CAS 160906-98-9)
- 2-(3-Chloro-1H-1,2,4-triazol-1-yl)butanoic acid (CAS 1795275-19-2)
- (S)-(2-Oxooxazolidin-4-yl)methyl 4-methylbenzenesulfonate (CAS 154669-49-5)
- 3-(4-Bromophenyl)propanenitrile (CAS 57775-08-3)
- 3-Methoxy-2-methyl-5-(methylthio)-6-nitropyridine (CAS 2794197-44-5)
- tert-Butyl 3-oxo-4-phenylpiperazine-1-carboxylate (CAS 845973-49-1)
- (5-Chloro-1-methyl-3-phenyl-1H-pyrazol-4-yl)methyl 4-nitrobenzoate (CAS 318234-22-9)
- 5-(Tert-butylsulfonyl)pyridin-2-amine (CAS 71167-98-1)
- H-Aib-OMe · HCl (CAS 15028-41-8)
- Vortioxetine Impurity 110 (CAS 27758-55-0)
- (E)-2-(5-bromo-2-methoxystyryl)-5-nitrobenzonitrile (CAS 301194-44-5)
- Liraglutide Impurity 5 TFA Salt (CAS CATO-C4X-19925)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com