3-methyl-3-[3-(trifluoromethyl)phenyl]pyrrolidine hydrochloride CAS 1781945-18-3
| CAS No. | 1781945-18-3 |
| Molecular Formula | C12H14F3N |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 265.70 g/mol gives 3-methyl-3-[3-(trifluoromethyl)phenyl]pyrrolidine hydrochloride distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies 3-methyl-3-[3-(trifluoromethyl)phenyl]pyrrolidine hydrochloride (CAS 1781945-18-3), a certified reference material (molecular formula C12H14F3NHCl, MW 265.70 g/mol) for analytical method development and quality control.
3-methyl-3-[3-(trifluoromethyl)phenyl]pyrrolidine hydrochloride (C12H14F3NHCl) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 3-methyl-3-[3-(trifluoromethyl)phenyl]pyrrolidine hydrochloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H14F3N HCl |
| Molecular Weight | 265.70 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1994 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related methyl Standards
- 3-(4-(Trifluoromethyl)phenyl)pyrrolidin-3-ol hydrochloride (CAS 1000198-74-2)
- 3-(4-(Trifluoromethyl)phenyl)pyrrolidine (CAS 1000198-76-4)
- (2-Methyl-4-(trifluoromethyl)thiazol-5-yl)methanol (CAS 1000339-72-9)
- methyl 3-((4-(trifluoromethyl)piperidin-1-yl)methyl)benzoate (CAS 1000339-86-5)
- methyl 4-(2-(4-(trifluoromethyl)piperidin-1-yl)ethoxy)benzoate (CAS 1000339-87-6)
- 2-(4-(trifluoromethyl)piperidin-1-yl)thiazole-5-carbaldehyde (CAS 1000339-88-7)
- 3-(2-(4-(trifluoromethyl)piperidin-1-yl)ethyl)benzaldehyde (CAS 1000339-89-8)
- 4-(2-(4-(trifluoromethyl)piperidin-1-yl)acetyl)-1H-pyrrole-2-carbaldehyde (CAS 1000339-90-1)
Recommended Standards
- 421-14-7 Methane, trifluoromethoxy- Ether, methyl trifluoromethyl Methyl perfluoromethyl ether Methyl trifluoromethyl ether Trifluoromethoxymethane Trifluoromethoxymethone (CAS 421-14-7)
- Ethyl 3-methyl-1-phenylpyrazole-5-carboxylate (CAS 81153-63-1)
- Kaurenoic acid (CAS 6730-83-2)
- 1-(Oxetan-3-yl)-3-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)urea (CAS 1260088-68-3)
- 4-(4-Fluorophenyl)piperazin-1-amine (CAS 935260-35-8)
- 4-Bromo-N-(3-methylpyridin-2-yl)benzamide (CAS 349125-17-3)
- 4-Acetamidobenzylamine (CAS 25412-53-7)
- (2S)-2-(4-chlorophenoxy)propan-1-ol (CAS 87810-51-3)
- Tert-butyl 3-(4-fluorophenyl)-3-hydroxypyrrolidine-1-carboxylate (CAS 1003560-58-4)
- (Ser(PO3H2)202,Thr(PO3H2)205)-Tau Peptide (194-213) trifluoroacetate salt (CAS 2022956-55-2)
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