8-Bromoimidazo[1,2-a]pyrazine-2-carboxylic acid CAS 1782021-97-9
| CAS No. | 1782021-97-9 |
| Molecular Formula | C7H4BrN3O2 |
| Molecular Weight | 242.03 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 242.03 g/mol gives 8-Bromoimidazo[1,2-a]pyrazine-2-carboxylic acid distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
8-Bromoimidazo[1,2-a]pyrazine-2-carboxylic acid (CAS 1782021-97-9) is a high-purity analytical reference standard with the molecular formula C7H4BrN3O2 and a molecular weight of 242.03 g/mol.
The molecular framework of 8-Bromoimidazo[1,2-a]pyrazine-2-carboxylic acid (C7H4BrN3O2) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, bromine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 8-Bromoimidazo[1,2-a]pyrazine-2-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H4BrN3O2 |
| Molecular Weight | 242.03 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1994 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 3 |
Related Bromoimidazo Standards
- 6-Bromoimidazo[1,2-α]pyrazine-2-carboxylic acid (CAS 1000018-56-3)
- 6-Bromoimidazo[1,2-a]pyrazine-8-carboxylic acid (CAS 1196154-13-8)
- 3-Bromoimidazo[1,2-a]pyrazine-8-carboxylic acid (CAS 1208082-43-2)
- 3-Bromoimidazo[1,2-a]pyrazine-6-carboxylic acid (CAS 1234015-04-3)
- 6-Bromoimidazo[1,2-a]pyrazine-3-carboxylic Acid (CAS 1404480-51-8)
- 8-Bromoimidazo[1,2-c]pyrimidine-3-carboxylic acid (CAS 1784316-04-6)
- 3-Bromoimidazo[1,2-a]pyrimidine-7-carboxylic acid (CAS 1784401-87-1)
- 1-Bromoimidazo[1,5-a]pyrazine-3-carboxylic acid (CAS 2171895-63-7)
Recommended Standards
- 2-Bromo-1H-imidazo[4,5-c]pyridine-6-carboxylic acid (CAS 1780641-03-3)
- 6-Bromo-1h-pyrazolo[3,4-b]pyridine-3-carboxylicacid (CAS 1782248-22-9)
- 7-Bromofuro[3,2-c]pyridine-2-carboxylic acid (CAS 1780391-64-1)
- 2-Bromopyrazolo[1,5-a]pyrimidine-6-carboxylic acid (CAS 1783552-72-6)
- 4-(1,3-Dihydro-isoindol-2-yl)-butyric acid hydrochloride (CAS 1185298-64-9)
- 4-Methylbenzimidazole Hydrochloride (CAS 1456821-64-9)
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