3-Bromo-5-fluoro-2-isopropoxybenzoic acid CAS 1782774-05-3
| CAS No. | 1782774-05-3 |
| Molecular Formula | C10H10BrFO3 |
| Molecular Weight | 277.09 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
3-Bromo-5-fluoro-2-isopropoxybenzoic acid (CAS 1782774-05-3), molecular formula C10H10BrFO3 and molecular weight 277.09 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 3-Bromo-5-fluoro-2-isopropoxybenzoic acid (C10H10BrFO3) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/bromine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), 3-Bromo-5-fluoro-2-isopropoxybenzoic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H10BrFO3 |
| Molecular Weight | 277.09 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1994 |
| Halogen Content | F/Br-containing |
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Recommended Standards
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- 1-Ethyl-3-methyl-3-imidazolium 4-Methylbenzenesulfonate (CAS 328090-25-1)
- L-Seryl-L-lysine (CAS 22677-61-8)
- N-Desmethyl Thebaine N-Carboxylic Acid Methyl Ester (1.0mg/ml in Acetonitrile) (CAS 220499-22-9)
- 3,5-dimethoxypyrazine-2-carbaldehyde (CAS 136866-38-1)
- Methyl 2-(3-bromophenyl)propanoate (CAS 80622-53-3)
- Thieno[2,3-c]pyridine hydrochloride (CAS 28783-40-6)
- 6-Chloro-3-(trifluoromethyl)picolinimidamide (CAS 1179533-95-9)
- 2-Chloro-3-fluorobenzyl Bromide (CAS 874285-19-5)
- Semaglutide impurity 107 (CAS CATO-C4X-2226107)
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