2-Ethyl-6-fluoro-1-methyl-1H-indole-3-carboxylic acid CAS 1782835-72-6
| CAS No. | 1782835-72-6 |
| Molecular Formula | C12H12FNO2 |
| Molecular Weight | 221.23 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies 2-Ethyl-6-fluoro-1-methyl-1H-indole-3-carboxylic acid (CAS 1782835-72-6), a certified reference material (molecular formula C12H12FNO2, MW 221.23 g/mol) for analytical method development and quality control.
The molecular framework of 2-Ethyl-6-fluoro-1-methyl-1H-indole-3-carboxylic acid (C12H12FNO2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO manufactures 2-Ethyl-6-fluoro-1-methyl-1H-indole-3-carboxylic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H12FNO2 |
| Molecular Weight | 221.23 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1994 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
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Recommended Standards
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- 2-(Pyrrolidin-3-yl)-1H-benzo[d]imidazole (CAS 756413-36-2)
- 4-(Difluoromethyl)-3-fluoro-6-iodopicolinaldehyde (CAS 1806875-50-2)
- Daclatasvir Impurity 29 (CAS CATO-C4X-184829)
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Why CATO?
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