2,4-Dichloro-6-ethyl-5-methylpyrimidine CAS 178307-27-2
| CAS No. | 178307-27-2 |
| Molecular Formula | C7H8Cl2N2 |
| Molecular Weight | 191.06 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 2,4-Dichloro-6-ethyl-5-methylpyrimidine is closely related to a nitrile group, chlorine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
2,4-Dichloro-6-ethyl-5-methylpyrimidine (CAS 178307-27-2), molecular formula C7H8Cl2N2 and molecular weight 191.06 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 2,4-Dichloro-6-ethyl-5-methylpyrimidine (C7H8Cl2N2) is characterized by a nitrile group, chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 2,4-Dichloro-6-ethyl-5-methylpyrimidine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H8Cl2N2 |
| Molecular Weight | 191.06 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2007 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Dichloro Standards
- (2,6-Dichloro-3-methylphenyl)hydrazine (CAS 1099660-40-8)
- 4,6-Dichloro-2-propylpyrimidine (CAS 1197-28-0)
- 2,6-Dichloro-N-ethylpyridin-4-amine (CAS 1314966-82-9)
- 4,5-Dichloro-2-methylbenzene-1,3-diamine (CAS 1375068-66-8)
- 4,5-Dichloro-6-ethyl-2-methylpyrimidine (CAS 141602-39-3)
- 2,3-Dichloro-5-ethyl-6-methylpyrazine (CAS 1461704-76-6)
- 3,5-Dichloro-2-methylbenzene-1,4-diamine (CAS 1513522-62-7)
- 4,6-Dichloro-5-ethyl-2-methylpyrimidine (CAS 175139-08-9)
Recommended Standards
- 2,6-dichloro-N,N-dimethylpyridin-4-amine (CAS 175461-34-4)
- 4,6-Dichloro-2-(propan-2-yl)pyrimidine (CAS 1850-98-2)
- (2,3-Dichlorobenzyl)hydrazine (CAS 51421-26-2)
- 4-Amino-3,5-dichlorobenzylamine (CAS 164648-75-3)
- 3-Ethynylbenzonitrile (CAS 171290-53-2)
- 3-Formyl-2-hydroxybenzoic Acid (CAS 610-04-8)
- 6-Chloro-8-(trifluoromethyl)quinolin-4(1H)-one (CAS 1065092-54-7)
- Methyl 5-bromo-1,4-dihydro-4-oxo-3-pyridinecarboxylate (CAS 1175512-08-9)
- Trifluoro(3-methoxypropyl)borate (CAS 1445947-65-8)
- 8-Bromo-3,7-dihydro-3-methyl-7-(phenylmethyl)-1H-purine-2,6-dione (CAS 93703-26-5)
- Methyl 4-(prop-2-yn-1-yloxy)benzoate (CAS 98260-05-0)
- Vazegepant impurity 35 (CAS CATO-C4X-320035)
- 2-(4-((((Benzyloxy)carbonyl)amino)methyl)piperidin-1-yl)acetic acid (CAS 1353972-16-3)
- (Ser(PO3H2)202,Thr(PO3H2)205)-Tau Peptide (194-213) trifluoroacetate salt (CAS 2022956-55-2)
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