4-Azetidin-3-yl-thiomorpholine-1,1-dioxide dihydrochloride CAS 178312-02-2
| CAS No. | 178312-02-2 |
| Molecular Formula | C7H14N2O2S |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 4-Azetidin-3-yl-thiomorpholine-1,1-dioxide dihydrochloride is closely related to an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
4-Azetidin-3-yl-thiomorpholine-1,1-dioxide dihydrochloride (CAS 178312-02-2) is a high-purity analytical reference standard with the molecular formula C7H14N2O2SHCl and a molecular weight of 226.72 g/mol.
The molecular framework of 4-Azetidin-3-yl-thiomorpholine-1,1-dioxide dihydrochloride (C7H14N2O2SHCl) is characterized by an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 4-Azetidin-3-yl-thiomorpholine-1,1-dioxide dihydrochloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H14N2O2S 2*HCl |
| Molecular Weight | 226.72 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 1.0 |
| CAS Registry Year (est.) | 2007 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Azetidin Standards
- 4-(Azetidin-1-yl)cyclohexan-1-amine dihydrochloride (CAS 1001347-27-8)
- 4-(Azetidin-1-ylmethyl)-1H-indole (CAS 1001395-40-9)
- 2-(Azetidin-1-yl)acetic acid (CAS 1008304-81-1)
- Azetidin-3-yl methylcarbamate hydrochloride (CAS 1009368-29-9)
- 5-(Azetidin-3-yl)-2-methyl-tetrazole (CAS 1009409-58-8)
- 2-((Azetidin-3-yloxy)methyl)-5-methyl-1,3,4-oxadiazole (CAS 1009409-61-3)
- Azetidin-3-yl methylcarbamate (CAS 1009409-62-4)
- 1-(Azetidin-3-ylmethyl)piperidine (CAS 1012784-24-5)
Recommended Standards
- 1-Bromo-2-Chloro-1,1,2-Trifluoroethane (CAS 354-06-3)
- 1-(2-Methylbenzyl)-1H-indole-3-carbaldehyde (CAS 428495-34-5)
- 3'-Ethylbiphenyl-3-carboxylic acid (CAS 1215206-74-8)
- 3-(5-Chlorobenzo[d]oxazol-2-yl)-7-hydroxy-2-oxo-2H-chromene-4-carbonitrile (CAS 97477-81-1)
- ethyl 3-bromo-2,2-difluoro-propanoate (CAS 111773-24-1)
- 1-(Benzo[d]thiazol-2-ylthio)propan-2-one (CAS 23385-34-4)
- 2-Ethoxyhexanoic Acid (CAS 100249-59-0)
- (2-Chloro-1,3-thiazol-5-yl)methyl 3-(2-chloro-6-fluorophenyl)-5-methyl-1,2-oxazole-4-carboxylate (CAS 478064-72-1)
- Vigabatrin EP Impurity A (CAS 7529-16-0)
- Insulin Degludec Impurity 12 (CAS CATO-C4X-215712)
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