tert-Butyl 8-fluoro-3,4-dihydroquinoxaline-1(2H)-carboxylate CAS 1783462-71-4
| CAS No. | 1783462-71-4 |
| Molecular Formula | C13H17FN2O2 |
| Molecular Weight | 252.28 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies tert-Butyl 8-fluoro-3,4-dihydroquinoxaline-1(2H)-carboxylate (CAS 1783462-71-4), a certified reference material (molecular formula C13H17FN2O2, MW 252.28 g/mol) for analytical method development and quality control.
The molecular framework of tert-Butyl 8-fluoro-3,4-dihydroquinoxaline-1(2H)-carboxylate (C13H17FN2O2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), tert-Butyl 8-fluoro-3,4-dihydroquinoxaline-1(2H)-carboxylate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C13H17FN2O2 |
| Molecular Weight | 252.28 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1994 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Recommended Standards
- tert-Butyl 5-fluoro-3,4-dihydroquinoxaline-1(2H)-carboxylate (CAS 1781430-98-5)
- tert-Butyl 7-fluoro-3,4-dihydroquinoxaline-1(2H)-carboxylate (CAS 1783932-66-0)
- 2-(3-Fluorophenyl)-2-(piperidin-3-yloxy)acetamide (CAS 1706454-85-4)
- Benzyl (3S,4S)-3-amino-4-fluoropiperidine-1-carboxylate (CAS 1792190-53-4)
- (2S,3R,4R,5S,6R)-3-(1,3-dioxoisoindolin-2-yl)-2-(ethylthio)-5-hydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-4-yl acetate (CAS 189188-19-0)
- N-[(2-phenyl-2H-1,2,3-triazol-4-yl)methylidene]hydroxylamine (CAS 6206-85-5)
- Chloro[(1,2,3,4,5,6-η)-2,2'',4,4'',6,6''-hexamethyl[1,1':3',1''-terphenyl]-2'-thiolato-κS][triisopropylphosphine-κP]ruthenium(II) (CAS 1621182-04-4)
- 4-Bromobut-2-yn-1-ol (CAS 13280-08-5)
- 1-(1-(Ethylsulfonyl)azetidin-3-yl)piperazine (CAS 1495720-37-0)
- 2-Benzylcyclohexane-1,3-dione (CAS 22381-56-2)
- tert-Butyl ((1-(2-aminoacetyl)piperidin-2-yl)methyl)(ethyl)carbamate (CAS 1353975-95-7)
- 2-Methyl-4-pivalamidobenzoic acid (CAS 1281876-01-4)
- Fenazaquin Impurity 3 (CAS 124428-11-1)
- Semaglutide impurity 76 (CAS CATO-C4X-222676)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com