1-Bromo-3,4-difluoro-2-methoxy-5-methylbenzene CAS 1783499-15-9
| CAS No. | 1783499-15-9 |
| Molecular Formula | C8H7BrF2O |
| Molecular Weight | 237.04 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
1-Bromo-3,4-difluoro-2-methoxy-5-methylbenzene (CAS 1783499-15-9), molecular formula C8H7BrF2O and molecular weight 237.04 g/mol, is a CATO reference standard with documented purity and traceability.
1-Bromo-3,4-difluoro-2-methoxy-5-methylbenzene (C8H7BrF2O) contains a hydroxyl group, an ether linkage, fluorine/bromine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 1-Bromo-3,4-difluoro-2-methoxy-5-methylbenzene meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H7BrF2O |
| Molecular Weight | 237.04 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1994 |
| Halogen Content | F/Br-containing |
Related Bromo Standards
- 1-bromo-4-(difluoromethoxy)-2-methylbenzene (CAS 1021172-76-8)
- 6-Bromo-2,3-difluorophenetole (CAS 1122410-43-8)
- 5-Bromo-2-ethoxy-1,3-difluorobenzene (CAS 115467-04-4)
- 1-Bromo-2-(difluoromethyl)-4-methoxybenzene (CAS 1214329-81-3)
- 3-Bromo-4-(difluoromethyl)anisole (CAS 1214379-79-9)
- 4-Bromo-2,6-difluoro-alpha-methylbenzyl Alcohol (CAS 1214900-62-5)
- 1-Bromo-4-(difluoro(methoxy)methyl)benzene (CAS 1236031-38-1)
- 1-Bromo-2-ethoxy-3,5-difluorobenzene (CAS 1242418-44-5)
Recommended Standards
- 2-(4-Bromophenyl)-2,2-difluoroethan-1-ol (CAS 1779939-06-8)
- (5-Bromo-2-(difluoromethyl)phenyl)methanol (CAS 1783499-28-4)
- (4-iodo-1-methyl-1H-pyrazol-3-yl)methanamine (CAS 1707568-56-6)
- 2-bromo-4-(difluoromethyl)-6-methylpyridin-3-amine (CAS 1803599-90-7)
- 4-(tert-Butyl)-3-cyclopropoxypicolinic acid (CAS 1243369-63-2)
- 5-Benzyl-5,8-diazaspiro[3.5]Nonan-7-one (CAS 1936128-66-3)
- (R)-tert-Butyl 3-(tert-butyl)piperazine-1-carboxylate (CAS 1240588-24-2)
- 3,5-Dimethoxypyridine hydrochloride (CAS 1334417-33-2)
- (Rac)-Hydnocarpin (CAS 51419-48-8)
- N-(4-Acetylphenyl)-4-(trifluoromethoxy)benzenesulfonamide (CAS 812651-86-8)
- (2-(Benzylthio)-4,5-dihydro-1H-imidazol-1-yl)(5-bromofuran-2-yl)methanone (CAS 851864-62-5)
- 1-(2,4-Bis(benzyloxy)-5-iodophenyl)ethanone (CAS 157953-16-7)
- 2-Boc-5-(2-Isopropylamino-thiazol-4-yl) -isoindoline (CAS 850877-62-2)
- Semaglutide impurity 25 (CAS CATO-C4X-222625)
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