3,5-Difluoro-4-methylbenzyl alcohol CAS 1783540-14-6
| CAS No. | 1783540-14-6 |
| Molecular Formula | C8H8F2O |
| Molecular Weight | 158.15 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 3,5-Difluoro-4-methylbenzyl alcohol.
3,5-Difluoro-4-methylbenzyl alcohol (CAS 1783540-14-6) is a high-purity analytical reference standard with the molecular formula C8H8F2O and a molecular weight of 158.15 g/mol.
3,5-Difluoro-4-methylbenzyl alcohol (C8H8F2O) contains a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 3,5-Difluoro-4-methylbenzyl alcohol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H8F2O |
| Molecular Weight | 158.15 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1994 |
| Halogen Content | F-containing |
Related Difluoro Standards
- 1,3-Difluoro-2-(methoxymethyl)benzene (CAS 110213-71-3)
- (1s)-2,2-Difluoro-1-phenylethan-1-ol (CAS 123986-75-4)
- 5,6-Difluoro-N1-methylbenzene-1,2-diamine (CAS 1248508-73-7)
- 3,5-Difluoro-4-methylanisole (CAS 1261478-94-7)
- 1,4-Difluoro-2-methoxy-5-methylbenzene (CAS 1261760-78-4)
- 2,2-Difluoro-2-phenylethanol (CAS 129973-51-9)
- (4,5-Difluoro-2-methylphenyl)methanol (CAS 1378624-91-9)
- (3,5-Difluoro-2-methylphenyl)methanol (CAS 1378666-27-3)
Recommended Standards
- (1S,2S)-2-(ethoxycarbonyl)cyclopropane-1-carboxylic acid (CAS 175415-95-9)
- 4-(2,2-Difluoroethyl)phenol (CAS 1784794-52-0)
- 2-[trans-2-methoxycarbonylcyclopropyl]acetic acid (CAS 175221-16-6)
- 1-[2-(Difluoromethyl)pyridin-3-yl]methanamine (CAS 1784794-66-6)
- 5-chloro-2-methyl-pyrazol-3-amine (CAS 167408-80-2)
- methyl 2-hydroxy-5-(2-(4-hydroxyphenyl)propan-2-yl)benzoate (CAS CATO-C3D-263098)
- 6-Fluoro-2-oxo-1,2,3,4-tetrahydroquinoline-4-carboxylic acid (CAS 869722-33-8)
- (4aS,5aR)-5,5-Difluoro-3-iodo-5a-methyl-1,4,4a,5,5a,6-hexahydrocyclopropa[f]indazole (CAS 2858743-20-9)
- 1,5-Diphenylpenta-2,4-dien-1-one (CAS 614-57-3)
- 2,5-Dihydroxy-1-methoxy-9H-xanthen-9-one (CAS 173220-32-1)
- N-(2-Fluorophenyl)-2-methoxybenzamide (CAS 5215-36-1)
- N-(3-(2-oxopropyl)-1,2,4-thiadiazol-5-yl)thiophene-2-carboxamide (CAS 693796-35-9)
- 1-(3-Morpholinopropyl)-5-oxopyrrolidine-3-carboxylic acid (CAS 842959-24-4)
- Fragment-[3-31]-Liraglutide (CAS CATO-C4X-199232)
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