Methyl 2-(1,1-dioxidotetrahydrothiophen-3-yl)-2,2-difluoroacetate CAS 1783700-24-2
| CAS No. | 1783700-24-2 |
| Molecular Formula | C7H10F2O4S |
| Molecular Weight | 228.21 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Methyl 2-(1,1-dioxidotetrahydrothiophen-3-yl)-2,2-difluoroacetate (CAS 1783700-24-2), molecular formula C7H10F2O4S and molecular weight 228.21 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of Methyl 2-(1,1-dioxidotetrahydrothiophen-3-yl)-2,2-difluoroacetate (C7H10F2O4S) is characterized by a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
As a certified reference material (CRM), Methyl 2-(1,1-dioxidotetrahydrothiophen-3-yl)-2,2-difluoroacetate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H10F2O4S |
| Molecular Weight | 228.21 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1994 |
| Halogen Content | F-containing |
| Sulfur Atoms | 1 |
Related Methyl Standards
- 1-(3-Methyl-1,1-dioxidotetrahydrothiophen-3-yl)-1H-pyrazole-4-carbaldehyde (CAS 1184038-95-6)
- N-(1,1-dioxidotetrahydrothiophen-3-yl)-N-methylmethanesulfonamide (CAS 898426-03-4)
- n-(1,1-Dioxidotetrahydrothiophen-3-yl)furan-2-carboxamide (CAS 324069-20-7)
- N-(1,1-dioxidotetrahydrothiophen-3-yl)-1H-imidazole-1-carboxamide (CAS 1087788-44-0)
- 1-(1,1-Dioxidotetrahydrothiophen-3-yl)-1H-pyrazole-4-carboxamide (CAS 251096-51-2)
- 5-(1,1-Dioxidotetrahydrothiophen-3-yl)-1,2,4-oxadiazole-3-carboxylic acid (CAS 1342868-72-7)
- 1-(1,1-Dioxidotetrahydrothiophen-3-yl)cyclopentane-1-carboxylic acid (CAS 1342952-50-4)
- (1,1-Dioxidotetrahydrothiophen-3-yl)(piperazin-1-yl)methanone (CAS 900641-32-9)
Recommended Standards
- 2-(5-(4-Nitrophenyl)-1H-pyrazol-3-yl)acetonitrile (CAS 175604-23-6)
- (3Z)-3-{[(1H-1,2,4-triazol-5-yl)amino]methylidene}-1,3-dihydro-2-benzofuran-1-one (CAS 338751-52-3)
- Trimethyl(2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)ethyl)silane (CAS 165904-20-1)
- (R)-3-(1-Aminoethyl)-5-(1,1-difluoroethyl)-4-fluorobenzonitrile (CAS 2917507-40-3)
- 2-(Benzo[d][1,3]dioxol-5-yl)-2-chloroacetonitrile (CAS 180330-90-9)
- 3-Allyl-4-fluorobenzo[d]thiazol-2(3H)-imine hydrobromide (CAS 2034154-95-3)
- 2-(3-Methylisothiazol-4-yl)acetic acid (CAS 10284-36-3)
- N-(3-fluoro-2-methylphenyl)formamide (CAS 153797-65-0)
- 4-Bromo-2-(methylthio)thiophene (CAS 87310-65-4)
- 2-(5-amino-3-methyl-4-nitro-1H-pyrazol-1-yl)ethan-1-ol (CAS 42098-29-3)
- 5-Chloro-7-methylisobenzofuran-1(3H)-one (CAS 118343-26-3)
- N-Methyl-1-(1-methyl-1h-pyrrol-2-yl)methanamine (CAS 26052-09-5)
- 3-Ethylphenyl isothiocyanate (CAS 4426-83-9)
- Neuropeptide S (rat) (CAS 412938-75-1)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com