4,4-Difluoro-3,5-dimethylpiperidine CAS 1783745-21-0
| CAS No. | 1783745-21-0 |
| Molecular Formula | C7H13F2N |
| Molecular Weight | 149.18 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 4,4-Difluoro-3,5-dimethylpiperidine is closely related to fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
4,4-Difluoro-3,5-dimethylpiperidine (CAS 1783745-21-0) is a high-purity analytical reference standard with the molecular formula C7H13F2N and a molecular weight of 149.18 g/mol.
The molecular framework of 4,4-Difluoro-3,5-dimethylpiperidine (C7H13F2N) is characterized by fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 4,4-Difluoro-3,5-dimethylpiperidine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H13F2N |
| Molecular Weight | 149.18 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 1.0 |
| CAS Registry Year (est.) | 1994 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Difluoro Standards
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Recommended Standards
- 3-(Difluoromethyl)-3-methylpiperidine (CAS 1780516-15-5)
- 1-(3,3-Difluorocyclopentyl)ethan-1-amine (CAS 1697951-90-8)
- β-(N-Acetoacetylamino)ethanol-d4 (CAS 1794960-21-6)
- (2,2-Difluorocyclohexyl)methanamine (CAS 1461715-53-6)
- 1,3-Difluoro-5-nitro-2-(trichloromethoxy)benzene (CAS 1417566-37-0)
- 10-amino-2-methyl-1H,4H-benzo[g]quinazolin-4-one (CAS 30507-35-8)
- 1-(5-BROMO-7-NITRO-2,3-DIHYDRO-INDOL-1-YL)-ETHANONE 1-ACETYL-5-BROMO-7-NITRO-2,3-DIHYDRO-1H-INDOLE 1-ACETYL-5-BROMO-7-NITROINDOLE 1-ACETYL-5-BROMO-7-NITROINDOLINE 62368-07-4 BC003234 N-ACETYL-5-BROMO-7-NITRO-INDOLINE (CAS 62368-07-4)
- 1-((4-Chloro-2,5-dimethoxyphenyl)sulfonyl)-3-methyl-1H-pyrazole (CAS 957354-66-4)
- 5,5'-(Benzo[c][1,2,5]selenadiazole-4,7-diyl) diisophthalic acid (CAS 1840869-92-2)
- 7-methyl-1,2,3,4-tetrahydroquinoline (CAS 58960-03-5)
- (3-Fluoro-5-methylphenyl)methanamine hydrochloride (CAS 1214344-22-5)
- [1-(6-Cyclopropylamino-pyrimidin-4-yl)-piperidin-3-yl]-methyl-carbamic acid tert-butyl ester (CAS 1353984-49-2)
- 7-(Diethylamino)-3-tosyl-2H-chromen-2-one (CAS 866341-20-0)
- Liraglutide Impurity 5 TFA Salt (CAS CATO-C4X-19925)
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