8-Fluoro-6-methyl-1,2,3,4-tetrahydroisoquinoline CAS 1783924-89-9
| CAS No. | 1783924-89-9 |
| Molecular Formula | C10H12FN |
| Molecular Weight | 165.21 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 165.21 g/mol gives 8-Fluoro-6-methyl-1,2,3,4-tetrahydroisoquinoline distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
8-Fluoro-6-methyl-1,2,3,4-tetrahydroisoquinoline (CAS 1783924-89-9) is a high-purity analytical reference standard with the molecular formula C10H12FN and a molecular weight of 165.21 g/mol.
The molecular framework of 8-Fluoro-6-methyl-1,2,3,4-tetrahydroisoquinoline (C10H12FN) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 8-Fluoro-6-methyl-1,2,3,4-tetrahydroisoquinoline under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H12FN |
| Molecular Weight | 165.21 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1994 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Fluoro Standards
- 8-Fluoro-3-methyl-1,2,3,4-tetrahydroquinoline (CAS 1017138-99-6)
- (R)-7-Fluoro-1,2,3,4-tetrahydronaphthalen-1-amine (CAS 1055949-62-6)
- (R)-6-Fluoro-1,2,3,4-tetrahydronaphthalen-1-amine (CAS 1057246-78-2)
- 8-fluoro-1-methyl-1,2,3,4-tetrahydroisoquinoline (CAS 1176414-86-0)
- 9-Fluoro-2,3,4,5-tetrahydro-1H-benzo[c]azepine (CAS 1185110-93-3)
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- (S)-5-fluoro-6-methyl-2,3-dihydro-1H-inden-1-amine (CAS 1212922-81-0)
Recommended Standards
- Benzo[d]thiazol-4-ylmethanol (CAS 1781692-33-8)
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- (3-methoxy-1,1-dioxo-thietan-3-yl)methanamine (CAS 1785196-99-7)
- 2-chloro Palmitic Acid (CAS 19117-92-1)
- Ethyl 2-(4-((aminothioxomethyl)amino)-3,5-thiazolyl)acetate (CAS 937623-27-3)
- 6-Chloro-2-methylisoindolin-1-one (CAS 58141-51-8)
- 2-(Isopropylamino)-1-(1-propyl-1h-pyrazol-5-yl)ethan-1-ol (CAS 1485888-95-6)
- 2-((2-Bromophenyl)amino)-4-methyl-1,3-thiazole-5-carboxylic acid (CAS 1071382-19-8)
- testas (CAS CATO-test18)
- 2-(Furan-2-yl)-1-methyl-1H-imidazole (CAS 32902-09-3)
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