3-(3-Fluorophenyl)-5,5-dimethyl-4-[4-(methylsulfonyl)phenyl]-2(5H)-furanone CAS 178402-36-3
| CAS No. | 178402-36-3 |
| Molecular Formula | C19H17FO4S |
| Molecular Weight | 360.40 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 3-(3-Fluorophenyl)-5,5-dimethyl-4-[4-(methylsulfonyl)phenyl]-2(5H)-furanone is closely related to a flavonoid core, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 3-(3-Fluorophenyl)-5,5-dimethyl-4-[4-(methylsulfonyl)phenyl]-2(5H)-furanone (CAS 178402-36-3), a certified reference material (molecular formula C19H17FO4S, MW 360.40 g/mol) for analytical method development and quality control.
The molecular framework of 3-(3-Fluorophenyl)-5,5-dimethyl-4-[4-(methylsulfonyl)phenyl]-2(5H)-furanone (C19H17FO4S) is characterized by a flavonoid core, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 3-(3-Fluorophenyl)-5,5-dimethyl-4-[4-(methylsulfonyl)phenyl]-2(5H)-furanone meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C19H17FO4S |
| Molecular Weight | 360.40 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2007 |
| Halogen Content | F-containing |
| Sulfur Atoms | 1 |
Related Fluorophenyl Standards
- 2-(4-(4-Fluorophenyl)-2-(hydroxymethyl)-1H-imidazol-5-yl)-N-isopropylthiazole-4-carboxamide (CAS 914266-57-2)
- 2-(4-(4-Fluorophenyl)-2-methyl-5-oxo-2,5-dihydro-1H-pyrazol-3-yl)-N-isopropylthiazole-4-carboxamide (CAS 914287-34-6)
- 4-(2-Fluorophenyl)-N-(4-nitrophenyl)piperazine-1-carbothioamide (CAS 756491-67-5)
- (5E)-3-(4-Fluorophenyl)-5-[(3-nitrophenyl)methylidene]-2-sulfanylidene-1,3-thiazolidin-4-one (CAS 300827-47-8)
- 4-[3-(4-Fluorophenyl)-3-oxo-1-propenyl]phenyl 2-phenylacetate (CAS 331460-78-7)
- 4-[3-(4-Fluorophenyl)acryloyl]phenyl 4-methylbenzenecarboxylate (CAS 329704-19-0)
- 5-Acetyl-3-[(4-fluorophenyl)methyl]-1-(4-methylpiperazin-1-yl)-1,2,3,4-tetrahydropyrimidine-2,4-dione (CAS 338399-28-3)
- 1-[4-(4-Fluorophenyl)piperazino]-3-(4-methoxyphenoxy)-2-propanol (CAS 439130-37-7)
Recommended Standards
- 4,4-(5,5-Difluoro-[1,1-biphenyl]-3,3-diyl)dimorpholine (CAS 1704068-67-6)
- (E)-3-(3,4-Bis(benzyloxy)phenyl)acrylic acid (CAS 179128-93-9)
- 160927-81-1 Phenanthro[3,2-b]furan-6(2H)-one,1,3,4,8,9,11b-hexahydro-5,7,11-trihydroxy-9-(hydroxymethyl)-4,4,11b-trimethyl-,(9R,11bR)- (CAS 160927-81-1)
- (3R,4S,5R,6R)-3,4-Bis(benzyloxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-2,5-diol (CAS 18933-71-6)
- GSK-2336805, >98% (HPLC) (CAS 1256390-53-0)
- N-(3,5-dichlorophenyl)-2-(1,1,2,2,3,3,4,4,5,5,6,6,6-tridecafluorohexyl)benzamide (CAS 680213-70-1)
- (hept-6-en-1-ylsulfanyl)methanimidamide hydrobromide (CAS 1909348-23-7)
- 3-(3-Nitrophenyl)-2-phenylacrylic acid (CAS 22161-41-7)
- Milnacipran impurity 33 (CAS 172016-06-7)
- 5-Aminouridine HCl salt (CAS 116154-74-6)
- (R)-1-(2-bromo-4-methylphenyl)ethan-1-amine (CAS 1213101-38-2)
- (3-Amino-2-methylphenyl)(2,4-dimethoxyphenyl)methanone (CAS 1225901-76-7)
- 1-methyl-2H-pyrrol-5-one (CAS 13950-21-5)
- Semaglutide impurity 45 (CAS CATO-C4X-222645)
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