1-Methyl-3-(2-oxo-2-(p-tolyl)ethylidene)piperazin-2-one CAS 178408-16-7
| CAS No. | 178408-16-7 |
| Molecular Formula | C14H16N2O2 |
| Molecular Weight | 244.29 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Based on its molecular formula C14H16N2O2, 1-Methyl-3-(2-oxo-2-(p-tolyl)ethylidene)piperazin-2-one contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 244.29 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
1-Methyl-3-(2-oxo-2-(p-tolyl)ethylidene)piperazin-2-one (CAS 178408-16-7) is a high-purity analytical reference standard with the molecular formula C14H16N2O2 and a molecular weight of 244.29 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C14H16N2O2 |
| Molecular Weight | 244.29 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2007 |
| Nitrogen Atoms | 2 |
Recommended Standards
- 1-{1-methyl-1H-pyrrolo[2,3-c]pyridin-3-yl}cyclopentane-1-carboxylic acid (CAS 1782697-71-5)
- 5,5-Dimethyl-2-(phenyldiazenyl)cyclohexane-1,3-dione (CAS 17867-43-5)
- Methyl 3-amino-1-((tert-butoxycarbonyl)amino)cyclobutane-1-carboxylate (CAS 1781611-40-2)
- [5-(benzyloxy)-6-methoxypyridin-2-yl]methanamine (CAS 1803562-77-7)
- [(S)-1-(2-Chloro-acetyl)-pyrrolidin-3-yl]-carbamic acid benzyl ester (CAS 1354002-36-0)
- N-(2-Bromo-4-fluoro-6-methylphenyl)hydrazinecarbothioamide (CAS 1303994-01-5)
- Methyl 2-methyl-6-morpholino-1H-benzo[d]imidazole-4-carboxylate (CAS 1372540-21-0)
- 3-(1,3-Dioxooctahydro-2H-4,7-methanoisoindol-2-yl)propanoic acid (CAS 355412-67-8)
- Ethyl 3-cyclopropyl-1-methyl-1H-pyrazole-5-carboxylate (CAS 133261-11-7)
- N-isopropyl-6-oxo-1,6-dihydropyridine-3-sulfonamide (CAS 1155056-68-0)
- Methyl2-(rel-(1r,5s,6s)-3-(2-chloro-6-(trifluoromethyl)pyrimidin-4-yl)-3-azabicyclo[3.1.0]hexan-6-yl)acetate (CAS 2102502-68-9)
- Cyclohexyl Isothiocyanate (CAS 1122-82-3)
- 3,3'-Bis[di(p-tolyl)amino]biphenyl (CAS 161485-60-5)
- (Glu1)-Fibrinopeptide B (human) (CAS 103213-49-6)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com