4-Chloro-6-(2-chlorophenyl)-2-methylpyrimidine CAS 178430-14-3
| CAS No. | 178430-14-3 |
| Molecular Formula | C11H8Cl2N2 |
| Molecular Weight | 239.10 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
4-Chloro-6-(2-chlorophenyl)-2-methylpyrimidine (CAS 178430-14-3) is a high-purity analytical reference standard with the molecular formula C11H8Cl2N2 and a molecular weight of 239.10 g/mol.
4-Chloro-6-(2-chlorophenyl)-2-methylpyrimidine (C11H8Cl2N2) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C11H8Cl2N2 |
| Molecular Weight | 239.10 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2007 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Chloro Standards
- 2-Chloro-4-(3-chlorophenyl)-5-methylpyrimidine (CAS 1341200-64-3)
- 4-Chloro-2-(3-chlorophenyl)-6-methylpyrimidine (CAS 180606-74-0)
- 3-Chloro-6-(4-chloro-3-methylphenyl)pyridazine (CAS 855784-90-6)
- 3-Chloro-6-[(2-chlorophenyl)methyl]pyridazine (CAS 339008-53-6)
- 3-Chloro-6-[(3-chlorophenyl)methyl]pyridazine (CAS 339008-51-4)
- 3-Chloro-6-[(4-chlorophenyl)methyl]pyridazine (CAS 339008-54-7)
- 4-Chloro-2-(4-chlorophenyl)-6-methylpyrimidine (CAS 66744-01-2)
- 4-Chloro-6-(2-chlorobenzyl)pyrimidine (CAS 405930-79-2)
Recommended Standards
- 1,1'-(Piperazine-1,4-diyl)bis(2-chloroethanone) (CAS 1703-23-7)
- 4,6-Dichloro-5-(p-tolyl)pyrimidine (CAS 146533-43-9)
- (E)-1,2,3,4,5-Pentafluoro-6-(2-nitrovinyl)benzene (CAS 207605-39-8)
- 6-(2,4-dichlorophenyl)pyridin-3-amine (CAS 1357165-68-4)
- (S)-1-(Benzo[d]thiazol-2-yl)ethan-1-amine (CAS 1169393-54-7)
- Ethyl 4-methyl-5-(phenylcarbamoyl)-2-(3,4,5-trimethoxybenzamido)thiophene-3-carboxylate (CAS 333774-49-5)
- 7aH-Imidazo[4,5-b]pyridin-7-amine (CAS 4261-04-5)
- 2-Bromo-3-(chloromethyl)-5-(difluoromethyl)isonicotinaldehyde (CAS 1805369-73-6)
- (R)-Tetrahydrofuran-2-carboxamide (CAS 539820-25-2)
- 2-amino-1-(3-methoxyphenyl)ethan-1-ol hydrochloride (CAS 53517-14-9)
- Ethyl 6-(4-cyanophenyl)-6-oxohexanoate (CAS 951885-69-1)
- 5-Chloro-3-ethyl-1H-1,2,4-triazole (CAS 39908-97-9)
- Esmolol Impurity 58 (CAS 23838-70-2)
- Semaglutide impurity 71 (CAS CATO-C4X-222671)
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