2-Amino-5-bromo-1H-indole-3-carboxylic acid CAS 1784331-41-4
| CAS No. | 1784331-41-4 |
| Molecular Formula | C9H7BrN2O2 |
| Molecular Weight | 255.07 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-Amino-5-bromo-1H-indole-3-carboxylic acid (CAS 1784331-41-4), molecular formula C9H7BrN2O2 and molecular weight 255.07 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 2-Amino-5-bromo-1H-indole-3-carboxylic acid (C9H7BrN2O2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 2-Amino-5-bromo-1H-indole-3-carboxylic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C9H7BrN2O2 |
| Molecular Weight | 255.07 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1994 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 2 |
Related Amino Standards
- 3-Amino-5-bromo-1H-pyrrolo[2,3-b]pyridine-2-carboxamide (CAS 1199590-78-7)
- 1-(2-AMino-5-bromo-1,3-benzoxazol-7-yl)ethan-1-one (CAS 1267630-39-6)
- 3-Amino-2,4-difluorobenzeneboronic acid pinacol ester, 97% (CAS 1315692-91-1)
- 3-Amino-4-bromobenzofuran-2-carboxamide (CAS 1823367-36-7)
- 3-Amino-6-bromobenzofuran-2-carboxamide (CAS 1823904-92-2)
- 3-Amino-7-bromobenzofuran-2-carboxamide (CAS 1823913-27-4)
- 3-Amino-5-bromobenzofuran-2-carboxamide (CAS 309922-87-0)
- 4-Amino-2,5-difluorobenzeneboronic acid pinacol ester, >97% (CAS 939807-75-7)
Recommended Standards
- 4-Bromo-1-methyl-1H-pyrrolo[3,2-c]pyridine-2-carboxylic acid (CAS 1784112-18-0)
- 4-(Bromomethyl)benzo[d]oxazole-2-carboxamide (CAS 1803834-59-4)
- 8-Bromo-1-methylimidazo[1,5-a]pyridine-3-carboxylic acid (CAS 1784009-44-4)
- Methyl 7-bromo-1H-benzo[d]imidazole-6-carboxylate (CAS 1803895-46-6)
- 3-Bromo-6-(cyclopentyloxy)-2-fluoropyridine (CAS 1881331-97-0)
- 3-(sec-Butoxy)-N-(3-propoxybenzyl)aniline (CAS 1040686-04-1)
- N-(2,6-dimethylphenyl)-2-morpholinoacetamide (CAS 75549-83-6)
- 5-Bromo-4-fluoro-2-nitrobenzaldehyde (CAS 213382-45-7)
- Methyl 6-chlorobenzo[d]isoxazole-3-carboxylate (CAS 50620-09-2)
- Spiro[benzo[d][1,3]dioxole-2,1'-cyclopentan]-5-amine hydrochloride (CAS 1047620-37-0)
- Vardenafil Impurity 54 (CAS 1810028-99-9)
- 1-Bromodecahydro-1,6-methanonaphthalene (CAS 57234-52-3)
- Pazopanib Impurity 41 (CAS 2095544-42-4)
- Semaglutide impurity 289 (CAS CATO-C4X-2226289)
Why CATO?
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